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The big question this week will be whether or not Michael Vick will play on Sunday, that much is obvious.
Vick suffered a bruised non-throwing hand, contrary to X-rays that at first signified a fracture.
If Vick can play through the pain, the Eagles will likely take this one in a cake walk.
But if he can't go, the Eagles could be in some trouble this week.
Vince Young would likely start if Vick couldn't go, and he's not nearly the same threat through the air or on the ground as Vick.
Then again—the 49ers are really, really bad and Alex Smith will probably get picked off at least a couple of times in this one.
Whether Vick plays or not, I'm rolling with Philly, for one reason—LeSean McCoy.
The man cannot be tackled. He fights for extra yards and dances his way out of tackles on nearly every play.
He's got 394 total yards through three games, and he'll tear up the 49ers on Sunday, too. He is a flat-out stud.
Prediction: Eagles 31, 49ers 14