These quarterbacks have so much talent and potential and can streak together impressive performances.
Or these guys can go the other extreme and play a really bad game.
Who else besides Cutler and Romo are the 10 most frustrating quarterbacks in the league?
Who is the most frustrating?
Read on to discover the answer.
Peyton Manning of the Indianapolis Colts is a stud, so why is the legendary quarterback on this list?
The reason is how God awful the Colts are without him.
With a severe neck injury sidelining Manning most to all of the season, the Colts are 0-7 and could have a 1-15 or 0-16 year, easily.
Indy is hoping to get Standford sensation Andrew Luck in the upcoming draft, but if Manning decides to come back the last few games, he would jeopardize the organization's chances of snagging his perfect successor.
Kevin Kolb was heralded as the biggest thing since swiss cheese last offseason, prompting the Arizona Cardinals to make a big trade with the Philadelphia Eagles to acquire him.
Kolb's media acclimation was somewhat unwarranted as he played 19 games (seven starts) with 319 pass attempts before the trade.
No. 4 has been severely average so far, and that's with top wide receiver Larry Fitzgerald on his team.
In 2011, he has 1,553 passing yards with seven touchdowns and seven picks. His passer rating is 78.8.
He also has six fumbles and three games with a sub-70 passer rating.
Philip Rivers is extremely talented, but he can be extremely frustrating.
The San Diego Chargers quarterback has great success in the regular season, but he tends to peter off come playoff time.
In seven-plus NFL seasons, Rivers has 21,376 passing yards for 143 touchdowns and a career passer rating of 95.9.
Rivers' playoff passer rating is 75.3 while leading the Chargers to a 3-4 record.
In 2011, Rivers is having his worst statistical year so far, even with tight end Antonio Gates and wide receiver Vincent Jackson
He has 1,715 passing yards for seven touchdowns but nine picks. His passer rating is 82.4.
Somehow, the New York Jets Mark Sanchez has had playoff success, going 4-2 in his first two seasons.
Sanchez, though, is not that good of a regular season quarterback.
Through two-plus seasons, he has 7,280 passing yards for 41 touchdowns and 39 interceptions. He has a 72.8 passer rating.
He is doing better this season, with 12 touchdowns against six picks, but he now has the services of wide receiver Plaxico Burress.
He can still have off games like Week 4's stinker against the Baltimore Ravens. Sanchez was 11-of-34 for 119 yards and a pick, good for a 30.5 passer rating.
McNabb's play has been declining to say the least. In 2011, he has 1,026 passing yards for four touchdowns and two interceptions, resulting in an 82.9 passer rating.
The Vikings fell to 1-5 under his leadership, and he was subsequently benched for rookie Christian Ponder in Week 7.
In 2010, McNabb underperformed for the Washington Redskins too. He had 14 touchdowns but 15 interceptions while the Redskins went 5-8 under his leadership.
Detroit Lions quarterback Matthew Stafford is one special player.
Yet, he continues to frustrate fans and teammates alike by not staying healthy.
Stafford was having a breakout year, throwing for 1,912 passing yards while having 16 touchdowns and four picks. He had a solid 95.5 passer rating.
This Sunday, Stafford was hit in the fourth quarter and limped off the field. He was found with a boot on his right foot and will have an MRI later today.
If Stafford is injured, Detroit's offense will suffer, as Shaun Hill is a big drop off from Stafford.
Stafford is no stranger to injury. He missed 23 games with knee and shoulder injuries. He had surgery to repair his right shoulder last year.
Jay Cutler of the Chicago Bears can be very frustrating to watch.
He has the arm strength to hit a receiver 50 or more yards out and can have pin-point accuracy. That ability has led him to throw over 3,000 yards the last four seasons.
Cutler has 1,702 passing yards for nine touchdowns and six picks, good for an 84.0 passer rating.
However, Cutler can have his stinkers. He has 11 career games with a sub-50 passer rating and a five-interception game in 2009 against the San Francisco 49ers.
Part of the problem is that Cutler does not have good receivers and has a horrible offensive line. Still, he isn't living up to his potential.
Washington Redskins quarterback Rex Grossman began the season as the starter and did well for awhile.
Now, the embattled quarterback is eating some bench behind a non-impressive John Beck.
"Sexy Rexy" had 596 passing yards for four scores and two picks the first two games, going 2-0 while posting a 90.6 passer rating.
Then, Grossman had 536 passing yards for two touchdowns and seven picks, including a horrible four-interception game against the Philadelphia Eagles. His passer rating those games was 45.45.
Nothing is different for Grossman, who has a career 70.4 passer rating and more picks (49) than touchdowns (46).
These stats are coming from the 2001 Heisman Trophy runner-up.
Eli Manning thinks he is an elite quarterback, but the New York Giant is more frustrating than brilliant.
Even though Manning has a Super Bowl ring and has a 101.1 passer rating this year, he has had an average career.
He has 30 games with a passer rating of 100 or more, and 22 games with a sub-60.
Manning can throw many touchdowns (167) but is also interception prone (118). In 2010, Manning threw a career-high 25 picks.
Dallas Cowboys quarterback Tony Romo is by far the most frustrating quarterback in the NFL.
Romo has been solid in the regular season, having a career 95.3 passer rating. He has 128 touchdowns against 68 interceptions while throwing for 18,046 yards.
The nine-year veteran has had top receivers in Terrell Owens, Miles Austin and tight end Jason Witten to throw to.
Romo's problem is crumbling when it counts.
This year, he threw two pick-sixs against the Detroit Lions that led to a giant collapse. He has 14 career games with two or more interceptions.
In the playoffs, Romo is 1-3, including mishandling the potential game-winning field goal in a 21-20 playoff loss to the Seattle Seahawks in 2007. He has a postseason passer rating of 80.8.