NFL Predictions Week 13: Odds, Spread and Picks for Entire Schedule

With any luck, bettors sit at 1-0 going into the bulk of Week 13 NFL odds.

Sure, it took a last-second Hail Mary on Thursday for bettors to ride the favored Green Bay Packers to a win, but the path traveled doesn't matter if the team does what's expected.

The rest of the slate shouldn't provide as much stress. There's divisional matchups and a handful of games with playoff implications, but this otherwise looks like one of the easier weeks to figure out, so long as bettors didn't take a bye week.

Here's a look at the full slate and a deep dive on a trio of can't-miss plays.

NFL Week 13 Odds

Game	Spread	O/U	Predicted Winner
Houston at Buffalo	BUF -3	41.5	HOU 24-17
San Francisco at Chicago	CHI -8.5	43.5	CHI 28-20
Cincinnati at Cleveland	CIN -10.5	43.5	CIN 30-13
Baltimore at Miami	MIA -3.5	42.5	MIA 23-14
Seattle at Minnesota	SEA -1	42	MIN 23-20
N.Y. Jets at N.Y. Giants	NYJ -1.5	46.5	NYJ 24-23
Arizona at St. Louis	ARI -4.5	43	ARI 35-20
Atlanta at Tampa Bay	E	46	TB 28-24
Jacksonville at Tennessee	TEN -1	43.5	TEN 20-13
Kansas City at Oakland	KC -2.5	44	OAK 24-20
Denver at San Diego	DEN -4	43	DEN 27-23
Carolina at New Orleans	CAR -7	50	CAR 33-28
Philadelphia at New England	NE -9.5	49	NE 32-17
Indianapolis at Pittsburgh	PIT -7.5	49	PIT 27-20
Dallas at Washington	WAS -4	42	WAS 23-14

Odds courtesy of Odds Shark. 

Last-Second Odds to Bet 

Arizona (-4.5) at St. Louis

This is where it gets easy for bettors. 

Earlier this week, the Arizona Cardinals were favorites by a touchdown against the rival St. Louis Rams, a number that also looked great given the circumstances.

Circumstances, as in, everything surrounding this matchup. Quarterback Carson Palmer and the Cardinals have won five games in a row at 9-2, even taking down the Seattle Seahawks and Cincinnati Bengals in that span behind his 27 touchdowns to nine interceptions.

On the flip side, the Rams have lost four in a row and will start Nick Foles under center, who in his last game tossed three interceptions in a 31-7 loss to those same Bengals.

Perhaps the only reason this line is close? Arizona took a loss at the hands of St. Louis back in Week 4. There's not much of a reason to put stock into that now, though, with the Cardinals on a tear and the Rams a shell of the former team that early in the season could pester contenders—they're now dropping games to teams such as the three-win Baltimore Ravens.

Palmer and the Cardinals know how to deal with the Rams. Expect them to pull away early and never really look back, fully avoiding any chatter about an upset by a spoiler.

Prediction: Cardinals 35, Rams 20

Cincinnati (-10.5) at Cleveland

Here's another divisional game with plenty of coin on the line for bettors who want as sure a thing as it gets this week. 

The Cincinnati Bengals won't have any problems on the road against the Cleveland Browns, a team they've already beat once this season in 31-10 fashion. There, the Bengals shut down Johnny Manziel while Andy Dalton threw a trio of scores, and the team rushed for 152 total yards.

Expect more of the same this weekend. Dalton's thrown just six interceptions on the season but two or more scores eight times. The defense behind him continues to play at an elite level, too, having held four of its last five opponents to 10 or fewer points.

The situation isn't as positive in Cleveland. Coach Mike Pettine will trot out Austin Davis under center, a player with 13 touchdowns, nine interceptions and four fumbles in 11 career appearances.

To show how desperate the Browns might be Sunday, Pettine mentioned that the team might trot out recently signed Terrelle Pryor, according to Around the NFL:

That's a terrible sign if there ever was one. Even if Cleveland discovers a way to move the ball on an elite defense, it cannot change the fact its unit allows 265.2 passing yards, 135.6 rushing yards and 28.2 points per game on average.

Cincinnati will blow the doors open early and relax.

Prediction: Bengals 30, Browns 13

Philadelphia at New England (-9.5)

Let's see, a 4-7 Philadelphia Eagles team, losers of three straight against a 10-1 New England Patriots team angry over their first loss of the season, an overtime affair on the road.

Yes, it pretty much writes itself.

Tom Brady and Co. might be without tight end Rob Gronkowski this weekend, but it won't matter much against a defense ranked 20th or worse in terms of yards surrendered on the ground and through the air.

Brady's still Brady with 28 touchdowns to four interceptions and returns home for this one. Perhaps the biggest hurdle is the Philadelphia offense, which coach Bill Belichick praised in the buildup to this game, according to ESPN.com:

"

Offensively it's probably as good a group of skill players as I've seen. They're at least two-deep and more really at some positions on the skill positions—quarterback, running back, tight end, receiver. They have a lot of good players at all those spots. They play multiple guys, they have great depth there and they keep bringing them at you.

"

There's a big difference between skill and execution, though. Philadelphia has lost three in a row while scoring no more than 19 points in a contest, and the team's only win since Week 6 came against the three-win Dallas Cowboys.

The Eagles look like the league's biggest free-falling team right now, so there's little reason to believe a miserable defense can somehow stop Brady. A hyped offense that hasn't shown up in more than a month doesn't figure to stand much of a chance against an improving New England defense, either, which finally returns linebacker Jamie Collins this week.

Look for the Patriots to vent their frustrations on the vulnerable Eagles. 

Prediction: Patriots 32, Eagles 17

Stats courtesy of NFL.com and accurate as of December 5. All advanced metrics courtesy of Pro Football Focus.