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Arian Foster, Texans
The Jets are the second-worst run defense in football, with running backs tearing up that unit for an average of over 130 yards a game. They've also scored six touchdowns. Back in 2010, Foster went for 143 total yards and two scores against the New York defense. That stat line might be the expectation Monday night for the AFC's second-leading rusher.
Marshawn Lynch, Seahawks
The Seahawks keep feeding Lynch (over 20 carries in all four games) and Lynch keeps producing. He's went over 80 yards in each game this season. The Panthers aren't a good run defense, and Pete Carroll will likely want to keep protecting Russell Wilson on the road. Expect at least 20 carries and 100 yards for Lynch, hopefully with a touchdown or two sprinkled in.
Adrian Peterson, Vikings
Already a top-three fantasy running back option? I think so. Peterson has been given 20 or more carries in back-to-back games, and the Tennessee run defense is allowing almost 130 yards a contest to opposing running backs. Peterson should be able to find the end zone at least once, especially at home.
Sleeper: Cedric Benson, Packers
The Packers are giving Benson a consistent work load, with 55 carries over the last three games. Benson is due for a 100-yard game with all the touches he's getting, and the Colts' run defense represents a perfect opportunity. 20-plus carries and a touchdown for Benson Sunday.