The Bills had a terrific start to the 2011 season, but have begun crumbling the last few weeks. Buffalo have been crushed in the last three games, and are quickly falling out of the playoff picture.
Facing a Jets team that is also in a must-win situation, the Bills will fail to come up big. Expect New York's vaunted defense to terrorize Ryan Fitzpatrick and shut down elite running back Fred Jackson for most of the game.
In the end, the inability to put pressure on Jets quarterback Mark Sanchez will cost the Bills the game, and their season, as they will fall to a lowly 5-6.
Jets 27, Bills 13
Ever since Tim Tebow took over as the Broncos starter, Denver has been 4-1. After a shocking win over the Jets last week, many are jumping on the Mile High bandwagon.
But a tough schedule and lack of a passing attack will doom John Fox and Company. With the Chargers on tap this week, followed by games with Super Bowl contenders such as the Bears and the Patriots, Denver should quickly fall out of the postseason race.
Tebow has been superb in the final minutes of games, but his inability to make strong and accurate throws will cost Denver against potent offenses like the Chargers, as they will be unable to match San Diego's frantic scoring.
Chargers 24, Broncos 17
The "Dream Team" once again places themselves in the playoff picture after a huge win over the divisional-rival Giants.
The Eagles possess enough talent and experience on both sides of the ball to make a run, but it is too little too late for the underachieving squad.
Despite last week's strong play, the Eagles will have trouble keeping up with the Patriots' prolific offense this week.
Philadelphia's offense won't go down without a fight against New England's weak secondary, but Tom Brady's unbelievable play will be too much to handle for Philadelphia's defense in the final minutes.
Patriots 31, Eagles 27