This is a game between two AFC heavyweight contenders and could become very important for seeding purposes as the playoffs approach.
The Steelers lead the series 14-11 overall, but the Patriots have won seven of the past nine matchups.
Both teams are currently in first place in their respective divisions, and both teams would likely drop into second place with a loss.
This one promises to be a thriller.
Let's take a look at the top five games in their history to help get in the mood for today's epic battle.