1) Andre Johnson vs. New Orleans Saints
This game is going to be a shootout, which plays well for fantasy owners of members of both teams.
Of all the talented wide receivers in the game, none are as talented as Johnson. He is the ideal receiver and has all the tools to dominate a game.
There is no doubt that he is Matt Schaub's favorite target, and with the Houston Texans having to score more than 30 points to win this one, Johnson should rack up plenty of catches, yards and touchdowns.
2) Calvin Johnson vs. Minnesota Vikings
If Calvin Johnson is good for two touchdowns while playing injured, imagine how many he will get when he is completely healthy this week against the Vikings?
It's no coincidence that both Johnson and Matthew Stafford are going to have huge fantasy weeks, as this duo appears to have some serious chemistry going between them right now.
Don't be surprised to consistently see Megatron as a top fantasy wide receiver every week of the season this year.
3) DeSean Jackson vs. New York Giants
I know Jackson has been disappointing so far this season, but so has the New York Giants' pass defense. Even without Michael Vick, I like Jackson to get plenty of fantasy points.
Whoever starts in place of Vick—Vince Young or Mike Kafka—is going to be playing it safe all game long.
That means short passes, including slants and screens, which happen to be Jackson's forte. If he can turn one or two short passes into huge gains, he will have a stellar fantasy week.
Surprise Missing Player: Larry Fitzgerald
Fitzgerald is playing against a much weaker team in the Seattle Seahawks, but the game is on the road and I still don't trust Kevin Kolb. It will be an average week for Fitzgerald.