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This will be a tough games for the Bills, and as the season progresses, this will be the case for most matchups. The Bills have been a struggling franchise for the last few years, and this year will be no different.
The Bills have improved their defense and are starting to head in the right direction, but they still have quite a few holes in their team.
When they come up against the Chiefs Week 1, there will be a lot problems for the Bills. Buffalo is outmatched in the quarterback position, as well as running back, receiver and most other skill positions. The Bills do have a strong pass defense, but that is about all they have going for them in 2011.
Look for the Bills to fall to the Chiefs 31-14 and go into Week 2 looking for a better result.