In the fourth quarter of this dramatic AFC South game, Manning passed one of the All-Time great quarterbacks, John Elway, making him third on the all-time list for career passing yards with 51,493 through his 13-year career.
On the day, Manning eclipsed 300 yards for the fourth consecutive game, connecting on 33 of 46 passes for 352 yards and two touchdowns. However, he threw his first interception of the season, although the pick wasn't entirely his fault.
However, that interception broke his 165 consecutive passes without throwing a pick.
After an outstanding performance by second-year wide receiver Austin Collie last week against the Denver Broncos, Manning turned to his favorite target, Reggie Wayne.
Manning connected with Wayne 15 times for 196 yards.
As for the all-time passing record, Brett Favre holds the No. 1 spot with 69,926, and Dan Marino at No. 2 threw for 61,361 in his career.
Garrard and Jones-Drew led the Jaguars down the field while the game was tied 21-21 in the fourth quarter, and ended the drive with an eight-yard touchdown pass to MJD to seemingly end the game.
However, Peyton Manning drove his team down the field and threw a touchdown pass to Austin Collie to tie the game with 48 seconds left.
The Jags drove down the field, with six plays resulting in 36 yards. With the clock winding down, it was up to kicker Josh Scobee to seal the deal.
He came through, booting a beautiful 59-yard field goal to win the game as time expired.