Jackson was hurt on a 2-yard carry midway through the second quarter while being hit by multiple Redskins defenders.
The two-time All-Pro tailback was down on the field for a substantial duration of time after being hit and he received prompt treatment on the Rams' sideline before heading into the locker room.
Despite only playing in the first half, Jackson had 58 yards on 10 carries and also scored a 42-yard touchdown.
In his seven years in the league, the former first-round selection has established himself as one of the premier running backs in the league. Regardless of his lack of supporting cast, he's been one of the few bright spots on a Rams team that's only managed to win six games in the past three seasons before Sunday.
He was expected to be the workhorse that No. 1 overall pick Sam Bradford could rely on in his rookie season as he gets accustomed to the league, and the two have formed a dynamic duo and are poised to be the foundation of the Rams' rebuilding process.
Jackson has had a relatively long medical history, so injuries are always a concern with him (missed ten games in the past three seasons). He's been asked to carry such a significant amount of workload over the years, that the wear and tear is catching up with him.
Making matters even worse, star safety O.J. Atogwe suffered a thigh injury as well.
Departing from reality, Jackson's injury is a tough blow to fantasy owners of him as he's been one of the top producers for several seasons now. It's never easy to lose a first-round pick to injury.
A timeline on his return has not been determined yet, and more information on the injury should be released soon.
Nonetheless, I wish Jackson a safe and speedy recovery and I hope he can return to action as soon as possible.
Information from an ESPN news report was used in this article.