In a game full of fantasy options, the Green Bay Packers and Houston Texans will take to the field at Reliant Stadium in Houston on Sunday night.
Whether you have these players on your roster or you are playing against them, a number of fantasy games stand to be won or lost by what unfolds.
Packers QB Aaron Rodgers and Texans RB Arian Foster are obvious starts, but the same can't be said for the rest of the players involved in tonight's action.
Let's make some sense of who can be counted on to produce and who should be avoided while you've still got time to adjust your lineup.
Start 'Em: Matt Schaub, QB, Houston Texans
The Packers pass defense ranks No. 16 in the NFL, allowing 230 yards through the air on average. But they've allowed 10 passing touchdowns—seventh most in the league—and Schaub is going to find the end zone at least once tonight, if not multiple times.
Sit 'Em: Alex Green/James Starks, RBs, Green Bay Packers
With Cedric Benson out of action for quite a while with a Lisfranc injury, the Packers figure to use a combination of Alex Green and James Starks (with some John Kuhn thrown in for good measure) in the backfield.
Neither back will do much against a Texans run defense that has yet to allow a rushing touchdown and gives up just over 85 yards per game on the ground.
Avoid all Packers running backs this week, regardless of their name.
Start 'Em: Randall Cobb, WR, Green Bay Packers
Houston's pass defense is among the best in the NFL, allowing fewer than 200 yards throwing per game and picking off more passes (seven) than they've allowed to find the end zone (six).
But Aaron Rodgers is going to put up numbers, and Randall Cobb is going to play a big part.
Greg Jennings is out again this week, meaning that Cobb is going to be one of Rodgers' primary targets (h/t ESPN).
Over the last two games, Cobb has caught 11 passes for 148 yards and a touchdown.
Cobb won't break 100 yards receiving for you, but he'll finish somewhere between 60 to 80 yards through the air with multiple receptions and have a realistic chance to reach the end zone.
Sit 'Em: Ben Tate, RB, Houston Texans
Coming into the season, Tate was a popular choice as a weekly flex option.
He's been banged up, but Texans coach Gary Kubiak is confident that Tate will be ready to go against the Packers:
Kubiak: Ben Tate practiced today, but it was a light day. I expect him to be ready Sunday. Jean practiced today.— Houston Texans (@HoustonTexans) October 10, 2012
Healthy or not, Arian Foster is going to get the bulk of the carries, and while Green Bay's run defense isn't great—they rank No. 17 in he NFL, allowing just over 117 rushing yards per game—they have only surrendered two rushing touchdowns on the season.
Between Green Bay's formidable front seven and the heavy workload that Foster is going to get, keep Tate on your bench in Week 6.