The last time the Patriots visited Buffalo (September 2011), wide receiver Wes Welker caught 16 balls for 217 yards and two touchdowns.
Here are my top 40 wide receivers for Week 4 (points-per-reception leagues).
This countdown simply identifies the weekend's best bets for catches, total yards, touchdowns and targets—a stat that must always factor into lineup strategies with receivers, tight ends and running backs.
When it comes to crafting a weekly listing of elite wide receivers, simply follow the trail of quarterbacks primed for Week 4 glory or the wideouts with track records of success against middling pass defenses.
To view this week's top-45 listing of wide receivers in standard-scoring leagues, click here.
Week 4: Top 40 PPR Wideouts
1. Calvin Johnson vs. Minnesota
2. Larry Fitzgerald vs. Miami
3. Andre Johnson vs. Tennessee
4. A.J. Green @ Jacksonville
5. Percy Harvin @ Detroit
6. Eric Decker vs. Oakland
7. Roddy White vs. Carolina
8. Dwayne Bowe vs. San Diego
9. Brandon Lloyd @ Buffalo
10. DeSean Jackson vs. N.Y. Giants
11. Marques Colston @ Green Bay
12. Vincent Jackson vs. Washington
13. Wes Welker @ Buffal
14. Victor Cruz @ Philadelphia
15. Julio Jones vs. Carolina
16. Hakeem Nicks @ Philadelphia
17. Steve Johnson vs. New England
18. Brandon Marshall @ Dallas
19. Steve Smith @ Atlanta
20. Miles Austin vs. Chicago
21. Demaryius Thomas vs. Oakland
22. Greg Jennings vs. New Orleans
23. Denarius Moore @ Denver
24. Jordy Nelson vs. New Orleans
25. Santonio Holmes vs. San Francisco
26. Jeremy Maclin vs. N.Y. Giants
27. Danny Amendola vs. Seattle
27a. Torrey Smith vs. Cleveland
28. Malcom Floyd @ Kansas City
29. Kenny Britt @ Houston
30. Lance Moore @ Green Bay
31. Sidney Rice @ St. Louis
32. James Jones vs. New Orleans
33. Nate Washington @ Houston
34. Nate Burleson vs. Minnesota
35. Michael Crabtree @ N.Y. Jets
36. Jerome Simpson @ Detroit
37. Mike Williams vs. Washington
38. Dez Bryant vs. Chicago
39. Brian Hartline @ Arizona
40. Leonard Hankerson @ Tampa Bay
40a. Brandon LaFell @ Atlanta
Jay Clemons can be reached on Twitter, day or night, at @ATL_JayClemons.