After taking a screen pass from Ryan Fitzpatrick up the field for about 25 yards, Spiller was tackled and landed directly on his left shoulder.
UPDATE: Monday, Sept. 24 at 12:49 p.m. EST by Brandon Galvin
CBS Sports' Jason La Canfora confirms that Spiller did not separate his shoulder in Week 3, though he is expected to miss 1-2 weeks.
RB CJ Spiller has sprained A/C joint, not separated shoulder. Great news for Bills Likely 1-2 week injury, Fred Jackson should play Sun— Jason La Canfora (@JasonLaCanfora) September 24, 2012
---END OF UPDATE---
UPDATE: Sunday, Sept. 23 at 6:50 p.m. ET by Richard Langford
Great news for Spiller. While it looks like he will not be able to play next week, the early prognosis is great.
The Buffalo News' Jay Skurski passed along some quotes from Chan Gailey. Gailey acknowledges that Spiller is "out for a week or two," but when asked if Spiller broke his collarbone, he replied "no."
UPDATE: Sunday, September 23 at 3:50 p.m. ET by Adam Wells
According to Jason La Canfora of CBS Sports, Spiller will undergo testing to determine the extent of damage in his shoulder on Monday.
Bills still gathering information on CJ Spiller's injured shoulder and an MRI is scheduled for Monday— Jason La Canfora (@JasonLaCanfora) September 23, 2012
Spiller's presence in the lineup, even if they get Jackson back, is critical. We have seen how much Spiller changes the running game when he is out there. Hopefully all the news comes back as well as can be expected.
--END OF UPDATE---
UPDATE: Sunday, September 23 at 2:10 p.m. ET by Adam Wells
Tim Graham of the Buffalo News is reporting that Spiller will not, in fact, return to the game due to a shoulder injury.
C.J. Spiller officially out for the rest of the game. Can't recall seeing somebody carted off the field and going back in.— Tim Graham (@ByTimGraham) September 23, 2012
Hopefully it is just a one-game injury because of the way Spiller has been playing, but we will have to await test results before knowing the full extent of the damage. It didn't look very good, so we shall see.
---END OF UPDATE---
As Pete Prisco of CBS Sports put it, ouch. It looked bad as soon as it happened, and Spiller was in a lot of pain.
Spiller down. Ouch. Looks like something up near pec muscle or shoulder.— Pete Prisco (@PriscoCBS) September 23, 2012
Tony Grossi of ESPN Cleveland reported that Spiller was carted off the field without a high possibility of return.
C.J. Spiller taken by golf cart to locker room. Doubt we'll see him again. Tashard Choice the replacement.— Tony Grossi (@TonyGrossi) September 23, 2012
Spiller has been the best thing to happen to the Bills offense in this young season. He was finally getting a real chance to show what he could do and looked like a star in the making.
If Spiller is out for a substantial amount of time, it is likely going to drastically alter the game plan for the Bills.
We will keep you updated on Spiller's injury and status as soon as more information becomes available.