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For the second time in four weeks the St. Louis Rams and San Francisco 49ers will meet in Week 13, but with a vastly different outcome.
Inside the friendly confines of their dome, the Rams can avoid the league's best rushing defense and allow Sam Bradford to spread the ball around to his receivers.
The 49ers were only average against the pass last season and any hope of beating them comes from an aerial assault.
St. Louis' top-10 passing defense will not fall victim to much of Alex Smith and the 49ers offense's play action attempts.
That means this upset will fall squarely on the Rams front-seven's ability to slow down San Francisco's rushing attack.
Most weeks this would be a poor proposition, but on this week, in this dome, it just might work.
It won't be a blowout, but St. Louis will win.