This week the 3-0 Buffalo Bills take on the 1-2 Cincinnati Bengals. The Bengals are a very different looking team this year than they were the last time these two franchises played, as wide receivers Terrell Owens and Chad Ochocinco have departed, as well as Carson Palmer.
Also out for this game will be the Bengals leading rusher, Cedric Benson, who is reportedly expected to miss the next three games due to a suspension resulting from an assault charge that occurred during the NFL lockout.
The Bills are looking to improve to 4-0 and take command of the AFC East division, while the young Bengals are trying to turn things around.
This slideshow takes a look at some of the key matchups that can make or break the outcome of this game.