Matt Garza takes the mound for the Cubs. Garza has a 4.43 ERA to go with a 1-4 record. In his only start against St. Louis, he gave up seven runs in 4.1 innings pitched.
Albert Pujols and Yadier Molina are both one-for-three against Garza, and Matt Holliday is two-for-nine.
Meanwhile, Jake Westbrook will try to regain some consistency for the Cardinals. He's had flashes of brilliance lately, but has overall been disappointing, sporting a 2-2 record with a 6.14 ERA and 1.75 WHIP.
The key matchup for Westbrook will be Cubs first baseman Carlos Peña, who has hit Westbrook to the tune of a .313 average with five doubles and four home runs.
The Cardinals come into the game with a 1.5 game lead on the Cincinnati Reds for first place. The Cubs trail St. Louis by five games, and will want to make up some ground if they hope to compete for the division title.
The weather at Wrigley is expected to be cloudy, with a chance of scattered thunderstorms and a game time temperature in the low-70s.
First pitch is scheduled for 7:05 CDT (8:05 EST).