Frank Gore is expected to miss the rest of the season after breaking his right hip during a Monday night game between the San Francisco 49ers and the Arizona Cardinals. The 49ers still went on to win 27-6.
The injury costs San Francisco its best offensive player and is a major blow to its chances of making the playoffs.
But they aren't out of it yet. Even with a 4-7 record, the 49ers are only one game behind both St. Louis and Seattle and have one game left against each team.
With five games remaining the 49ers have an opportunity to avenge their 0-5 start to the season and capture the NFC West title. However, they'll have to do it without their leading rusher.
Here's a look at the five players who must step up in Gore's absence to give San Francisco a chance at making the playoffs.