Alright, so this one wasn't hard to figure out, but it doesn't stop me from doing it anyway. Peyton Manning will have the biggest game of the week if not the season.
The Colts will be in Washington to take on the Redskins on Sunday night, and will Manning have a great time. The Redskins have arguably the worst pass defense in the league, ranked 30th in that category.
In Week 2, the Redskins gave up nearly 500 passing yards to the Texans' Matt Schaub, a quarterback in the same division as Manning, but who's not as good. Manning has better receivers and is just a better quarterback than Schaub at this point—so imagine what he'll do.
The game against the Texans was also in Washington, so it's not as if something will change at home. This game could be a shootout between Manning and Donovan McNabb, but Manning is the one who'll shine in the Sunday night spotlight.