Every time I think about Frank Gore, one word comes to mind- Beast.
Gore may be the best RB in the entire NFL, having the ability to slam the ball on the inside, having hands like a WR, and being able to block in the backfield like a tackle. Gore is a rare breed of RB, and it rarely to never that he has a bad game. Coach Singletary has made it a point to make the 49ers a running team, and Gore if the guy to do it.
The Eagles defense has had a very difficult time stopping the rushing game, and Gore will abuse them up and down the field. Unless, the Eagles come into the game prepared to slow down Gore. That's right. There is literally no way to stop Frank Gore, your best bet is just to try to slow him down.
The Eagles currently have the 27th ranked run defense, which is something the Gore has been eyeing up all week. If the Eagles allow Gore to run the ball consistently, they will lose. This is the most important aspect in the Eagles walking out of this game as winners.
I have this feeling in the pit of my stomach that the night will go one of two ways. Path #1- The Eagles defense comes prepared and limits Gore to minimal yardage, forcing the 49ers to rely on Alex Smith. Path #2- The Eagles defense continues to struggle stopping the run, allowing Gore to lead the 49ers to victory.
My guess is Reid is drilling the defense 100% on run defense, because he knows how Gore can tear apart a defense. This should be an interesting to see how the Eagles respond to Gore, seeing how he is the biggest factor in this game.
I think everything combined, Gore, an away game, and no Vick, will just prove to be to much for the Eagles to overcome. Unfortunately, there really is little chance that Kolb will do well enough to squeak out a victory through pure offensive force. The defense more than likely won't be able to contain Gore, allowing the 49ers to manage the clock to their liking, and put up enough points to win.
Final Prediction: Eagles- 17 49ers- 28