Many injuries have happened so far this year, but there are plenty of players to make up for it.
Players like Ryan Grant, Reggie Bush, Knowshon Moreno and Ryan Matthews have all taken blows and on the shelf right now.
Performance has also been a big factor in replacements as well. We have already seen Kevin Kolb, Jason Campbell, Matt Moore, and Trent Edwards all lose their starting jobs.
Michael Vick has been a goldmine for people who took a shot on him on the wire. Here are the best waiver-wire pick-ups for Week 3: