There's no doubt that each NFL franchise wants to start the new season strong with all of their players fully energized and ready to go.
Unfortunately that's not always the case, as injuries and other absences can derail a team from playing at their maximum potential.
With that in mind, here's my ranking of the top 15 players who may be unavailable for the 2010-2011 season opener in order of the impact their loss could have.
Note: Most of the players on this list will miss time due to injury, and their rehibiliation period is a mere estimate. I also didn't include players who are projected to miss time well into the regular season.