Injuries are a fact of life in the National Football League—and an infuriating part of fantasy football.
The games haven't even started yet, and already a top-five pick has clouds of doubt swirling around him. The top rookie running back in fantasy this year may see his season ended before it begins. Two top-10 wideouts may not be ready for the start of the year. A top-three tight end may begin the year on the PUP list.
Other than that, everything's fine!
These injuries only underscore the importance of having a viable plan B in place, and many times that involves handcuffing.
No, not that kind of handcuffs. Get your mind out of the gutter and pay attention.
Handcuffs are simply the backups for high draft picks or oft-injured players. Usually that means running backs, but the strategy can also be employed with other positions.
With that in mind, here's a look at some of the biggest injuries from around the NFL and the player who can best fill the breach if these stars aren't ready for Week 1.
Note: This article was modified from its original form to reflect the Patriots-Lions preseason game and the Steelers trading for Felix Jones.