The $64 question, of course, is where does this leave Lotulelei when April's draft rolls around?
That's a loaded question, and one that frankly can't be answered with any sort of certainty given the information currently at our disposal.
The most important thing, of course, is Lotulelei's health.
As has been tragically shown by the cases of players such as Gaines Adams, it's not unheard of for a young man seemingly in top physical shape to die suddenly from a previously undiagnosed heart condition.
The comparison wasn't lost on Ralph Mancini of NFL Draft Bible.
Terrible news re: Star Lotulelei. His heart condition will bring 1 name 2 mind: Gaines Adams. We're not talking abt bones & ligaments here.
— Ralph Mancini (@ReverendRalph) February 25, 2013
For now, let's take an optimistic view and assume that Lotulelei's career isn't in jeopardy and that his condition is either temporary or manageable.
It's still hard to imagine a scenario in which this doesn't adversely affect his draft stock.
It may not be fair, but as I said before, there may well already be teams pulling Lotulelei off their draft boards. More will all but certainly follow suit if this turns out to be anything more than dehydration.
Odds are, as things stand right now, Lotulelei's chances of being a top five (or even top 10) pick in April's draft are all but gone.
In a draft this deep on the defensive line most teams just aren't going to be willing to take that risk.
Now it's more a matter of waiting to see the results of further testing, because until those results are in we won't know just how far Lotulelei is going to fall.
Who knows? The player we're talking about now as a medical red flag may be the same guy we mention three years from now as a huge steal after he dropped into some team's lap.
For Lotulelei's sake I hope so.