NFL Picks Week 4: San Francisco 49ers and 2 Other Underdogs Who'll Cover

Vegas has grossly disrespected several underdogs this week and is going top pay dearly for it. Huge and unwarranted spreads are going to draw plenty of action for the underdogs, and some favorites expected to win big aren't just going to cover, they're going to lose outright.

Here are three underdogs who will cover with ease on Sunday. (Note: lines according to bodog.com)

San Francisco 49ers (+9)

Mike Vick is banged up, the Eagles aren't the explosive team they were last season on offense, and their free-agent acquisitions can't disguise their miserable run defense. DeSean Jackson has made it clear that he's not willing to put his body on the line, and all is not sunny in Philadelphia.

The 49ers have a shutdown defense and though the offense is struggling, this week will present the perfect opportunity for Kendall Hunter and a banged-up Frank Gore to really get it going on the ground en route to a huge upset on the road.

Oakland Raiders (+5.5)

The Raiders hate the Patriots. Hate is a strong word, but with the tuck-rule debacle, it applies. Yes, they are still bitter about it. Richard Seymour also has to be thrilled that he gets a chance to get back at the team who shipped him away.

Darren McFadden is going to carve up the Patriots' porous defense and Jason Campbell doesn't have to fear a miserable Pats' pass defense. The Raiders can win this game in a shootout and even if they don't, a five-point differential is too big of a spread.

Seattle Seahawks (+5.5)

The Seahawks have one of the best home-field advantages in the league. They take on a more talented Saints team and the Seahawks aren't off to the start they wanted to be, but they shouldn't be written off.

The Falcons are coming off an embarrassing loss to the Bucs that came at the hands of a boneheaded offsides penalty. The Falcons are struggling to find an offensive identity and as long as Tarvaris Jackson limits his mistakes, this is going to be close throughout.