The last eight encounters between the clubs have seen the Blues take seven victories and they will hope to continue that record on the weekend.
Despite the apparent class that Roberto Mancini's side have shown this season with their attacking achievements, their draw to Fulham last weekend proved that they can be beaten or nearly so.
David Moyes is a master at pulling together a team that can challenge anyone, and he has shown to be a crafty strategist over the last few seasons due to the teams limited of any available funds for him to strengthen.
Baines had this to say about the weekend game:
It is a big game for us at the weekend because City have been doing well but we will take confidence from the results we have had against them in the past.
We will draw on that. We have a tough run of games over the next few weeks so it was important we kept our momentum going [with the win over West Brom in the Carling Cup].
My hope is for a game as great as the one last week with the Toffees finding a way to beat their rivals who are the stronger on paper.