Who could forget the drama of last seasons fixture, Liverpool saving a draw with the latest goal ever scored in Premier League football.
Many pundits predict that three Champions League places are already decided upon with both Manchester clubs and Chelsea battling for position only.
That leaves Arsenal and Liverpool the consensus choices to fight for that last remaining Champions League berth and both teams have a similar need at the heart of their defense.
Arsenal have needed a central defender for years, yet manager Arsene Wenger seems quite happy to spend his transfer money on wingers as recent arrival Alex Oxlade-Chamberlain shows.
However, Arsenal fans are being to ask serious questions of their managers transfer ability, and it would seem that this is finally the season that Wenger plunges into the transfer market for the commanding centre-back Arsenal so desperately need.
Liverpool, on the other hand, need a changing of the guard.
Jamie Carragher is not getting any younger and Daniel Agger and Martin Skrtel is not a partnership to strike fear in the hearts of opposing strikers.
Manager and fan-favourite Kenny Dalglish has shown that he does have money behind him in this transfer window, as Stewart Downing and Jordan Henderson have already been welcomed to Anfield after £20 million moves.
With both teams renewing their rivalry on the pitch this weekend, it seems that both will be rivals in the transfer market.
Here are six central defenders both clubs should be looking at.