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Chelsea's Brazilian defender David Luiz reacts during the English Premier League football match between Middlesbrough and Cheslea at Riverside Stadium in Middlesbrough, northeast England on November 20, 2016.
Chelsea won the match 1-0. / AFP / Lindsey PARNABY / RESTRICTED TO EDITORIAL USE. No use with unauthorized audio, video, data, fixture lists, club/league logos or 'live' services. Online in-match use limited to 75 images, no video emulation. No use in betting, games or single club/league/player publications.  /         (Photo credit should read LINDSEY PARNABY/AFP/Getty Images)
Chelsea's Brazilian defender David Luiz reacts during the English Premier League football match between Middlesbrough and Cheslea at Riverside Stadium in Middlesbrough, northeast England on November 20, 2016. Chelsea won the match 1-0. / AFP / Lindsey PARNABY / RESTRICTED TO EDITORIAL USE. No use with unauthorized audio, video, data, fixture lists, club/league logos or 'live' services. Online in-match use limited to 75 images, no video emulation. No use in betting, games or single club/league/player publications. / (Photo credit should read LINDSEY PARNABY/AFP/Getty Images)LINDSEY PARNABY/Getty Images

EPL Week 13 Predictions: Premier League Picks, Key Players and Fixtures

Rory MarsdenNov 22, 2016

Premier League leaders Chelsea take on London rivals Tottenham Hotspur at Stamford Bridge in the headline match of Week 13 on Saturday. 

With Liverpool and Manchester City, who play Sunderland and Burnley, respectively, just one point behind the Blues in the standings, Chelsea will be desperate to claim all three points to ensure they remain top of the pile.

Meanwhile, fourth-placed Arsenal host Bournemouth on Sunday, while Manchester United take on out-of-form West Ham United at Old Trafford.

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Read on for a closer examination of some of the key players to look out out for over the weekend's action, along with a full fixture list and predictions.

DateTime (GMT/ET)FixturePrediction
Nov. 2612:30 p.m./7:30 a.m.Burnley vs. Manchester City1-3
Nov. 263 p.m./10 a.m.Hull City vs. West Bromwich Albion0-1
Nov. 263 p.m./10 a.m.Leicester City vs. Middlesbrough2-2
Nov. 263 p.m./10 a.m.Liverpool vs. Sunderland3-1
Nov. 263 p.m./10 a.m.Swansea City vs. Crystal Palace1-0
Nov. 265:30 p.m./12:30 a.m.Chelsea vs. Tottenham Hotspur1-1
Nov. 27midday/7 a.m.Watford vs. Stoke City2-1
Nov. 272:15 p.m./9:15 a.m.Arsenal vs. Bournemouth2-0
Nov. 274:30 p.m./11:30 a.m.Manchester United vs. West Ham United2-1
Nov. 274:30 p.m./11:30 a.m.Southampton vs. Everton1-1

David Luiz, Chelsea 

Chelsea's serene progress to the top of the table has come due to a six-game winning streak in which they have netted 17 goals and conceded none.

Their last outing against Middlesbrough returned a 1-0 victory in a scrappy affair and, once again, Antonio Conte's back three of David Luiz, Gary Cahill and Cesar Azpilicueta were exemplary, per Michael Cox in the Guardian.

Per Cox, Luiz was the standout performer for Chelsea against Boro as he dealt admirably with Alvaro Negredo, while also displaying his quality in possession as he set up several Blues attacks from deep.

The Brazilian centre-back has been a revelation this season:

Chelsea's decision to buy him back from Paris Saint-Germain in the summer was met with widespread uncertainty given his historic positional ill-discipline and unpredictability.

However, Luiz has been brilliant in the main since Conte switched to a 3-4-3 system and will be essential when Chelsea face Spurs on Saturday.

Harry Kane will need to be well guarded having netted a late double to earn Mauricio Pochettino's side a victory last time out against West Ham, while his distribution from deep will be valuable again as Chelsea try to unlock Spurs' staunch defence.

Previously, relying on Luiz, 29, to pull out a top performance would have been a risky business, but after his recent heroics in Chelsea's back line it would be no surprise if he proves the standout player again on Saturday. 

Juan Mata, Manchester United 

United have not won a Premier League home game since their 4-1 demolition of Leicester City in late September.

Since then, they have drawn with Stoke City, Burnley and, most recently, Arsenal, Olivier Giroud's late headed goal a hammer blow for Jose Mourinho's side, who looked to be heading for all three points.

MANCHESTER, ENGLAND - NOVEMBER 19: Juan Mata of Manchester United in action during the Premier League match between Manchester United and Arsenal at Old Trafford on November 19, 2016 in Manchester, England.  (Photo by Michael Regan/Getty Images)

It was Juan Mata who had put United 1-0 ahead against the Gunners in the 68th minute—finishing a fine move with a deft finish—and the Spaniard has arguably been the Red Devils' best player in 2016-17.

Given the summer arrivals of Paul Pogba and Zlatan Ibrahimovic, the Spaniard's prominence for the Red Devils is something of a surprise.

His consistent excellence, on the other hand, is no shock, as he has been one of the finest operators in the Premier League since joining Chelsea in 2011, per Sky Football:

Against a struggling West Ham who currently lie just a point above the relegation zone, Mata, 28, will again be vital.

As well as getting into scoring positions himself, the Spaniard also brings all United's other attacking threats—Ibrahimovic, Marcus Rashford, Anthony Martial—into play.

If he has another good game at Old Trafford on Sunday, then United have an excellent chance of claiming a much-needed home win against a Hammers side that have conceded 23 goals already this season in 12 matches. 

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