There is no doubt where the game of the Premier League programme will be this weekend.
Liverpool play host to Chelsea on Sunday, where victory for the home side will end the Blues' hopes of winning the title while enhancing the dreams of the Anfield club.
Indeed, Liverpool could effectively be champions if Manchester City lose at Crystal Palace following the game at Anfield.
Arsenal and Everton continue their chase for fourth spot. The Toffees open the Premier League weekend with their trip to Southampton on Saturday, while the Gunners entertain out-of-form Newcastle United on Monday.
Here's the latest team news for the Premier League weekend.
Southampton vs. Everton
Southampton will be without long-term absentees Gaston Ramirez and Jay Rodriguez, while Morgan Schneiderlin is also out.
Everton will be without defender Sylvain Distin and midfielder Kevin Mirallas for the game. They join long-term casualties Steven Pienaar, Bryan Oviedo, Darron Gibson and Arouna Kone on the sidelines.
|Southampton vs. Everton|
Fulham vs. Hull City
Scott Parker, Mahamadou Diarra and Kieran Richardson are set to return for Fulham, but Kostas Mitroglou remains sidelined.
Shane Long returns for Hull City, and Sone Aluko could feature. Allan McGregor, Paul McShane and Robbie Brady in the treatment room.
|Fulham vs. Hull City|
Stoke City vs. Tottenham Hotspur
Stoke City are waiting on Erik Pieters, who has been suffering with a virus this week.
Michael Dawson and Jan Vertonghen could return for Spurs.
|Stoke City vs. Tottenham Hotspur|
Swansea City vs. Aston Villa
Swansea striker Michu is rated doubtful.
Christian Benteke and Libor Kozak remain sidelined for Aston Villa.
|Swansea City vs. Aston Villa|
West Bromwich Albion vs. West Ham United
Gareth McAuley could return for West Brom, but Liam Ridgewell and Zoltan Gera miss out.
West Ham manager Sam Allardyce has a full squad to choose from, bar Marco Borriello.
|West Bromwich Albion vs. West Ham United|
Manchester United vs. Norwich City
Rafael and Robin van Persie are all out for Manchester United in Ryan Giggs' first game in charge as interim manager.
Elliott Bennett is expected to return for Norwich, but Joseph Yobo is still missing.
|Manchester United vs. Norwich City|
Sunderland vs. Cardiff City
Sunderland striker Connor Wickham is a slight doubt, but Ki Sung-Yueng, Steven Fletcher and Carlos Cuellar are still out.
Craig Bellamy is expected to return after illness for Cardiff, but Craig Noone and Mark Hudson are still out.
|Sunderland vs. Cardiff City|
Liverpool vs. Chelsea
Liverpool manager Brendan Rodgers will make a late decision on the inclusion of Daniel Sturridge, but Jose Enrique is still out.
Petr Cech and John Terry have joined the Chelsea casualty list, along with Samuel Eto'o, while Eden Hazard is also missing
|Liverpool vs. Chelsea|
Crystal Palace vs. Manchester City
Marouane Chamakh is set to return for Crystal Palace, who have no other injury concerns.
Yaya Toure could return for Manchester City, while Jesus Navas faces a late fitness test. David Silva is ruled out.
|Crystal Palace vs. Manchester City|
Arsenal vs. Newcastle United
Kieran Gibbs is doubtful for Arsenal, but Thomas Vermaelen could feature. Jack Wilshere, Theo Walcott and Serge Gnabry remain on the sidelines, while Abou Diaby has a groin problem.
Luuk de Jong and Moussa Sissoko face late fitness tests, while Hatem Ben Arfa is also doubtful for Newcastle.
|Arsenal vs. Newcastle United|