Wojnarowski added it's possible James could miss additional games beyond Friday. James and the Lakers will monitor the injury and plan to take the cautious approach as the postseason nears, per Wojnarowski.
Largely because James and Anthony Davis have missed significant time with injuries, the Lakers are in a dog fight to avoid slipping into the NBA's play-in tournament for the playoffs. At 37-28, the reigning champions are fifth in the Western Conference but sit just one game ahead of the seventh-place Blazers.
Despite being without Davis, Los Angeles was in second place before James suffered a high ankle sprain in a 99-94 loss to the Atlanta Hawks on March 20. The four-time MVP was out for 20 games, and the Lakers slipped down the standings.
James was back for two games before the ankle became a problem again.
General manager Rob Pelinka surrounded James and Davis with a strong supporting cast, retaining many of the key players from last year's squad and addressing the notable departures.
Los Angeles' hopes of a title repeat, however, appear to rest squarely on James' return.