The Eastern Conference-leading Cleveland Cavaliers (29-11) will try to beat the Los Angeles Clippers (27-14) for the third consecutive time both straight up and against the spread when they square off on Thursday night.
Cleveland is a 5.5-point betting favorite at sportsbooks monitored by Odds Shark.
The Cavaliers have already lost to the top two Western Conference teams over the past week, getting routed 132-98 by the defending NBA champion Golden State Warriors as 3.5-point home favorites on Monday.
The Clippers currently sit in the fourth spot in the West and saw their season-high 10-game winning streak come to an end with a 110-103 loss to the Sacramento Kings as four-point home favorites last Saturday.
They rebounded from that setback with a 140-132 overtime victory against the Houston Rockets as five-point home chalk on Monday behind a career-high 40 points from shooting guard J.J. Redick.
Los Angeles connected on a franchise-record 22 three-pointers in the win, with Redick making nine of his 12 attempts.
Cleveland rebounded from its most lopsided loss of the year versus Golden State in a rematch of the 2015 NBA Finals by beating the Brooklyn Nets 91-78 as a 13-point road favorite on Wednesday.
Cavs forward Kevin Love scored only three points and six rebounds against the Warriors but had 17 and 18, respectively, at Brooklyn. LeBron James also scored 17 points, and both he and Love got to sit during the fourth quarter.
The Cavs have won 10 of their last 12 games overall to go along with a 5-5-2 mark ATS, according to the Odds Shark NBA Database.
This will be the first meeting between Los Angeles and Cleveland this season, with the latter sweeping two games last year. The Clippers are just 3-14 SU and 4-13 ATS in the past 17 meetings dating back to 2007, with the under cashing in four of the last five.
The Cavs have not performed particularly well when playing the second game of a back-to-back lately, going 3-3 SU and 1-4-1 ATS in their previous six.
It is also worth noting that the under is 5-0 the last five times they have played the second game of a back-to-back and 3-1 in their past four overall.