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This year, to all intents and purposes, appears to be the year of the changing guard. Such has been the maturity and efficiency with which the club's abundance of youthful talent have set about asserting their claims to the throne, that the future for Ryan Giggs, Rio Ferdinand et al, in a football sense, appears brief.
That being said, with the injury to Chris Smalling, quite possibly ruling him out of contention, I feel the defensive emphasis, will be placed on experience to counteract the threat of Liverpool’s attacking surfeit.
Phil Jones, since joining the club, has been a revelation, and at only 19 years old, appears to be a very strong contender for future England captain. Yet United-Liverpool at Anfield is a different animal.
With this in mind I can see Sir Alex preferring the tried and tested defensive partnership of Vidic and Ferdinand to shackle Suarez and Carroll.
At left back Patrice Evra is a shoe-in for the role, as he has been for much of the season.
The dilemma that could arise is at right back. With no obvious first choice at the club (in the way Evra is at left-back), Smalling, Jones, Rafael and Fabio have all been afforded an opportunity in the berth.
Currently of the aforementioned quadruplet, only Jones and Fabio, natural centre and left-backs respectively, are fit and realistically available for selection. However, continuing with this emphasis on the experience of the back four I can see a less obvious choice getting the nod.
With the heroic early season form of Nani and Ashley Young, Antonio Valencia, the standout star of the back end of last year has become the forgotten man of Old Trafford. Although a natural right winger by trade, the former Wigan man is also adept as an emergency right back. With pace to burn and something most definitely to prove, Valencia could well be the choice come Sunday.