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MANCHESTER, ENGLAND - SEPTEMBER 10:  Zlatan Ibrahimovic of Manchester United shoots during the Premier League match between Manchester United and Manchester City at Old Trafford on September 10, 2016 in Manchester, England.  (Photo by Clive Brunskill/Getty Images)
MANCHESTER, ENGLAND - SEPTEMBER 10: Zlatan Ibrahimovic of Manchester United shoots during the Premier League match between Manchester United and Manchester City at Old Trafford on September 10, 2016 in Manchester, England. (Photo by Clive Brunskill/Getty Images)Clive Brunskill/Getty Images

EPL Table: 2016 Standings After Saturday's Week 4 Results and Top Scorers

Tom SunderlandSep 10, 2016

Zlatan Ibrahimovic's quest for the 2016-17 Premier League Golden Boot advanced on Saturday after he scored in the Manchester derby, but his strike wasn't enough to prevent Manchester United suffering a 2-1 defeat to Manchester City.

City manager Pep Guardiola watched as his side pulled off a masterful victory over their local rivals to extend their winning start to the campaign and clinch a temporary three-point cushion at the top of the standings.

LONDON, ENGLAND - SEPTEMBER 10:  Santi Cazorla of Arsenal celebrates scoring his sides second goal with his team mates during the Premier League match between Arsenal and Southampton at Emirates Stadium on September 10, 2016 in London, England.  (Photo by

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In the evening fixture, a brace of goals from Roberto Firmino along with strikes from Sadio Mane and Adam Lallana saw Liverpool to a 4-1 win over reigning champions Leicester City, with Jamie Vardy scoring the Foxes' only consolation.

Elsewhere, Arsenal pounced in injury time to collect a 2-1 win against Southampton, while north London rivals Tottenham Hotspur clinched a much more expansive 4-0 demolition of Stoke City at the Bet365 Stadium.

Crystal Palace also jumped on the London win wagon with their 2-1 defeat of Middlesbrough thanks to a maiden club goal from Christian Benteke, but West Ham United couldn't follow suit, surrendering a 2-0 lead over Watford to lose 4-2.

Read on for a breakdown of Saturday's biggest Premier League headlines, complete with a look at the latest standings and all the Week 4 results thus far.

Manchester United1-2Manchester City
Arsenal2-1Southampton
Bournemouth1-0West Brom
Burnley1-1Hull City
Middlesbrough1-2Crystal Palace
Stoke City0-4Tottenham Hotspur
West Ham United2-4Watford
Liverpool4-1Leicester City
1Michail AntonioWest Ham4
2Zlatan IbrahimovicManchester United4
3Etienne CapoueWatford3
4Sergio AgueroManchester City3
5Santi CazorlaArsenal2
6Diego CostaChelsea2
7Eden HazardChelsea2
8Jermain DefoeSunderland2
9Cristhian StuaniMiddlesbrough2
10Philippe CoutinhoLiverpool2
1Manchester City4400114+712
2Chelsea330072+59
3Manchester United430173+49
4Tottenham422072+58
5Liverpool421197+27
6Arsenal421186+27
7Hull421153+27
8Everton321042+27
9Middlesbrough41214405
10Watford411278-14
11Crystal Palace411234-14
12West Bromwich Albion411223-14
13Bournemouth411235-24
14Burnley411235-24
15Leicester411247-34
16Swansea310224-23
17West Ham410359-43
18Southampton402236-32
19Sunderland301235-21
20Stoke4013210-81

Mourinho and Guardiola's Manchester Legacy

After months spent in agonising wait, Premier League audiences were finally treated to their first showdown between the managerial duo of Jose Mourinho and Pep Guardiola—and the fixture didn't disappoint.

Kevin De Bruyne enjoyed a man-of-the-match performance as he bagged the opener, before Kelechi Iheanacho collected what would go on to be the winner, leaving travelling fans in fine voice, per NBC's Joe Prince-Wright:

Ibrahimovic scored his fourth goal in four Premier League games for United and halved the deficit right before the break, but it wasn't enough to stop the Red Devils suffering their first loss of the campaign.

It was a fiery encounter from start to finish, precisely the tempo one would like to expect from a Manchester derby, and not every player came away from the fray unscathed, via TalkSport:

Guardiola came out on top of this occasion, but former El Clasico rival Mourinho will be hoping to return to the Etihad Stadium in February to secure his redemption.

Uncertain performances from the likes of Paul Pogba and Daley Blind saw United stutter in front of their home fans, particularly in the first half, while the absence of Sergio Aguero didn't stop City's progress.

Londoners Thrive in Foreign Territory

Tottenham Hotspur's English striker Harry Kane (2L) scores his team's fourth goal  during the English Premier League football match between Stoke City and Tottenham Hotspur at the Bet365 Stadium in Stoke-on-Trent, central England on September 10, 2016. /

All three London clubs playing away from home found success on Saturday, as Tottenham, Watford and Palace saw off respective opponents Stoke, West Ham and Middlesbrough with varying ease.

It's taken four games of the 2016-17 campaign, but Spurs were also particularly pleased to see last season's Golden Boot-winner, Harry Kane, finally bag his first of the season, and a landmark strike to boot:

He was joined on the scoresheet by Dele Alli and Heung-Min Son, the latter of whom rewarded manager Mauricio Pochettino for his show of faith with a brace of goals at the Bet365 Stadium.

Meanwhile, Walter Mazzarri's Watford side persevered to snatch a 4-2 win from their trip to the London Stadium, and Squawka detailed precisely how the shift of the fixture weighed back in their favour:

Michail Antonio notched a brace of goals, but the Hammers let their foot off the gas as Odion Ighalo, Troy Deeney, Etienne Capoue and Jose Holebas all bagged to secure the Hornets a valuable win.

Benteke opened the scoring for the Eagles before Wilfried Zaha turned from provider into scorer himself, meaning Daniel Ayala's initial equaliser from Boro counted for little in the end. 

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