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Argentina haven't managed to progress past the quarterfinal stage of the World Cup since they finished runners-up at Italia '90.
However, the side currently ranked third by FIFA are generally being considered third-favorites to triumph at the home of their fiercest rivals.
Aside from the aforementioned narrow penalty-shootout defeat to Brazil in the Superclásico de las Américas, the Albiceleste have not lost a match since an October 2011 World Cup qualifier in Venezuela.
With eight CONMEBOL qualification matches remaining, Alejandro Sabella's side sit comfortably at the top of the standings.
Not only will Argentina have the geography on their side—South American sides always do well in South America—but they boast one of the strongest lineups in years.
Sergio Aguero, Gonzalo Higuain and Ezequiel Lavezzi are just some of the spoils they offer upfront. Javier Mascherano, Angel di Maria and Ever Banega are world-class midfield options, while a defence commanded by Pablo Zabaleta and Fabricio Coloccini is nothing to be sniffed at.
Oh, and they also happen to have the best player in the world as their captain.
This will be Leo Messi's best chance to win a World Cup, the honor that many believe he needs to win to be considered the best player of all time.