Premier League Fixtures: Week 6 Schedule, Score Predictions for EPL Matchday

After falling to their first Premier League defeat of 2016-17 against Liverpool in Week 5, Chelsea will look to get back to their winning ways under manager Antonio Conte when they travel to north London to face Arsenal. 

Manchester United are also desperately in need of three points, having lost three games on the bounce in all competitions, but they face the tough task of hosting defending champions Leicester City at Old Trafford.

Meanwhile, Manchester City can continue their perfect record under manager Pep Guardiola with a win at Swansea City.

Here's a look at the full schedule for Week 6, along with score predictions:

Date	Time (BST/ET)	Fixture	Prediction
Saturday, Sept. 24	12:30 p.m./7:30 a.m.	Manchester United vs. Leicester City	2-1
Saturday, Sept. 24	3 p.m./10 a.m.	Bournemouth vs. Everton	1-2
Saturday, Sept. 24	3 p.m./10 a.m.	Liverpool vs. Hull City	3-0
Saturday, Sept. 24	3 p.m./10 a.m.	Middlesbrough vs. Tottenham Hotspur	0-1
Saturday, Sept. 24	3 p.m./10 a.m.	Stoke City vs. West Bromwich Albion	1-1
Saturday, Sept. 24	3 p.m./10 a.m.	Sunderland vs. Crystal Palace	1-2
Saturday, Sept. 24	3 p.m./10 a.m.	Swansea City vs. Manchester City	1-3
Saturday, Sept. 24	5:30 p.m./12:30 p.m.	Arsenal vs. Chelsea	2-2
Sunday, Sept. 25	4 p.m./11 a.m.	West Ham United vs. Southampton	1-2
Monday, Sept. 26	8 p.m./3 p.m.	Burnley vs. Watford	0-2

Preview 

Clashes between Arsenal and Chelsea are invariably feisty affairs. The Blues won both Premier League duels between the two sides last term, with Arsenal seeing three players sent off across the two matches.

Discipline will be vital for Arsene Wenger's side on Saturday, as the Gunners will have little chance of taking any points from the match if they are reduced to 10 men.

The key man for Chelsea will likely be striker Diego Costa, who has netted five goals in as many league games so far in 2016-17.

Tony Marshall/Getty Images

He was on the scoresheet for the Blues last time out as they lost 2-1 at home to Liverpool and could be lethal against Arsenal's inconsistent defence, as the Gunners have already conceded seven goals in 2016-17.

Unlike Chelsea—who go into Saturday's clash on the back of the Liverpool defeat and a draw with Swansea in the league—Arsenal are in excellent form, having won three games on the bounce.

Per WhoScored.com, Alexis Sanchez was brilliant in Arsenal's 4-1 win over Hull City in their last outing:

Given the Chilean is arguably Arsenal's most potent attacker, his form will be crucial to how the Gunners fare against Chelsea.

The match could be decided by how well the defenders deal with Costa and Sanchez.

United will need some inspiration if they are to beat Leicester after following up a decent performance in their defeat to City with underwhelming losses to Feyenoord in the UEFA Europa League and Watford in the Premier League.

Morale is clearly low, and manager Jose Mourinho has some big decisions to make if he is going to turn United's form around, per the Times' Oliver Kay:

Unlike United—who won their opening three games of the new league season—the Foxes have followed a poor start to the campaign with a recent upturn in form.

Having been hammered 4-1 by Liverpool, Leicester's two most recent results were a 3-0 defeat of Club Brugge in the UEFA Champions League and a 3-0 win over Burnley last time out in the Premier League.

Given the respective form of both sides, Claudio Ranieri's men should be confident of at least claiming a draw, but United will surely be buoyed by being back in front of their home fans.

OLI SCARFF/Getty Images

Meanwhile, Guardiola's City side continue to look mighty impressive. They dispatched Bournemouth 4-0 with ease last time out in the league.

Kevin De Bruyne, Raheem Sterling and Kelechi Iheanacho are all in fine form, and in further bad news for Swansea, Sergio Aguero is set to return from his suspension in time for the Saturday trip to the Liberty Stadium.

Swansea have had a tough start to the new season and have not won in the league since opening day, so a home win would be a huge shock in Week 6, given City's impressive form so far.