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SOUTH BEND, IN - SEPTEMBER 15:  Ian Book #12 of the Notre Dame Fighting Irish breaks away from  Dayo Odeyingbo #10 of the Vanderbilt Commodores
at Notre Dame Stadium on September 15, 2018 in South Bend, Indiana.  (Photo by Jonathan Daniel/Getty Images)
SOUTH BEND, IN - SEPTEMBER 15: Ian Book #12 of the Notre Dame Fighting Irish breaks away from Dayo Odeyingbo #10 of the Vanderbilt Commodores at Notre Dame Stadium on September 15, 2018 in South Bend, Indiana. (Photo by Jonathan Daniel/Getty Images)Jonathan Daniel/Getty Images

Notre Dame, Clemson Among Favorites in College Football Week 4 Odds

Tyler ConwaySep 16, 2018

If the early lines are any indication, the oddsmarkers aren't too keen on Notre Dame pulling out a blowout in Week 4.

The Irish open as 6.5-point favorites against unranked Wake Forest next week, per OddsShark. Notre Dame's shaky start to the season shifted what probably would have been a double-digit line if the teams met in Week 1. 

The Irish are yet to defeat a team by more than eight points despite only playing one ranked opponent and not leaving the friendly confines of South Bend. Wake Forest is coming off a home loss to Boston College.

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Clemson, which dropped a spot in the rankings to No. 3 this week, opens as 16-point favorites on the road against Georgia Tech. 

Georgia Tech is coming off a 24-19 loss to Pittsburgh.

Here's a look at some notable matchups:

No. 3 Clemson (-16) at Georgia Tech

Tulane at No. 4 Ohio State (-34)

Army at No. 5 Oklahoma (-31.5)

No. 7 Stanford at No. 20 Oregon (-1.5)

Arkansas at No. 9 Auburn (-27.5)

No. 10 Penn State (-27) at Illinois

Kansas State at No. 12 West Virginia (-14)

No. 14 Mississippi State (-11) at Kentucky

Texas Tech at No. 15 Oklahoma State (-12)

Florida Atlantic at No. 16 UCF (-13)

No. 17 TCU at Texas (pick)

No. 18 Wisconsin (-3) at Iowa

Florida International at No. 21 Miami (-28)

No. 23 Boston College (-7) at Purdue 

No. 24 Michigan State (-4.5) at Indiana

Florida (-6) at Tennessee

The only Top 10 team that enters this week as an underdog is Stanford, which faces off against No. 20 Oregon. The Ducks are 3-0 but have faced a cupcake schedule thus far. 

Stanford has already picked up a win over USC this year but will be playing its first game on the road. 

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