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🚨 Mitchell Headed to 1st Conference Finals

2025 Week 14 College Football Picks, Predictions for Every Game

David KenyonNov 26, 2025

It all comes down to this.

Across the college football world, "it" can mean different things. Some programs are fighting for the best College Football Playoff résumé possible. Others have a trip to their conference championship game at stake.

But remember to look beyond the major headlines, too.

At some programs, a new single-season win record is possible. Bowl eligibility is also on the line for a staggering 21 teams holding a 5-6 mark—and Army at 5-5. Plus, it's rivalry week! Coveted trophies and bragging rights are up for grabs.

Yes, both conference races and the Playoff hunt are destined to attract the most attention. There's so much more to watch in Week 14, though.

Rankings are based on the CFP Top 25.

See our latest picks here.

Top Matchups for Week 14

1 of 5
COLLEGE FOOTBALL: NOV 22 Rutgers at Ohio State
Julian Sayin

No. 4 Georgia (10-1) vs. No. 23 Georgia Tech (9-2), Friday, 3:30 p.m. ET

Georgia Tech's postseason dreams ended in unceremonious fashion last weekend. Now, it's a test of the Jackets' resilience. Can they flip a mindset from front-runner to spoiler? I don't doubt Brent Key's ability to motivate, but I have concerns about Tech's defense bouncing back against a steady UGA offense—particularly since this matchup is at Mercedes-Benz Stadium, not GT's campus.

Prediction: Georgia 34, Georgia Tech 24

No. 3 Texas A&M (11-0) at No. 16 Texas (8-3), Friday, 7:30 p.m.

Texas, similarly, is aiming to end Texas A&M's perfect year. The question is quite simple: Will UT bother playing defense again? One of the stingiest units in the country early on, the Horns have yielded 31-plus points in four straight games. Their offense is showing life, yes, but A&M is built to capitalize on a reeling defense. Texas' shot at an upset hinges on a reversal. Possible! Not what I'll pick.

Prediction: Texas A&M 38, Texas 31

No. 1 Ohio State (11-0) at No. 15 Michigan (9-2), Noon

If you're in the "believe it when I see it" category, I don't blame you. Michigan had a mediocre team in 2024 and still beat Ohio State—in Columbus. Outside of home-field advantage, there is simply no good reason for U-M to spring an upset. The offense is more surviving than thriving, and OSU's defense hasn't surrendered more than 16 points at all this season. I'm going to take Ohio State. And I will not be surprised (how could you be?) if the stats don't matter yet again.

Prediction: Ohio State 27, Michigan 13

No. 12 Miami (9-2) at No. 22 Pitt (8-3), Noon

All right, Pitt, are you bringing the first-half version or the second-half team? Pitt soared to a 28-0 lead in its upset of Georgia Tech but vanished on offense after the break, hanging on for a 42-28 win because of a 100-yard pick-six. The escapability of someone like Pitt QB Mason Heintschel is always a nuisance for Miami's defense, but the 'Canes should be able to claw out an ugly victory.

Prediction: Miami 26, Pitt 23

No. 14 Vanderbilt (9-2) at No. 19 Tennessee (8-3), 3:30 p.m.

You ready for points? Both programs boast a top-10 mark in points per game. This is a final opportunity for Vandy QB Diego Pavia to bolster his Heisman Trophy résumé, and he'll likely have another impressive box score. Vandy, though, doesn't often force turnovers—which is usually the main issue for UT in losses. Avoid those, and the Vols win at home.

Prediction: Tennessee 37, Vanderbilt 30

Thursday and Friday Games

2 of 5
Indiana v Maryland
Fernando Mendoza

No. 7 Ole Miss (10-1) at Mississippi State (5-6), Friday, Noon ET

The circus is part of The Lane Kiffin Experience. I think he's a great coach! Ole Miss has been incredibly fun to watch! But, man, this ongoing flirtation with Florida and LSU must be exasperating to the team. There's a genuine chance Ole Miss wastes a golden chance to reach the CFP. Mississippi State's offense is a genuine threat here. I'll stick with Ole Miss, but that's not a comfortable choice.

Prediction: Ole Miss 33, Mississippi State 27

No. 13 Utah (9-2) at Kansas (5-6), Friday, Noon

In the escape of the season, Utah stayed alive in the Big 12 race because it crawled out of a late 12-point hole against Kansas State. Similar theatrics should not be necessary at Kansas, which hasn't topped 20 points—save for a matchup with a broken Oklahoma State team—since Week 6.

Prediction: Utah 34, Kansas 17

No. 2 Indiana (11-0) at Purdue (2-9), Friday, 7:30 p.m.

Should be simple for Indiana. Purdue has dropped nine consecutive games and hasn't defeated a power-conference team all season. Rivalries can be weird, but an upset in West Lafeyette would be downright shocking.

Prediction: Indiana 42, Purdue 17

Navy (8-2) at Memphis (8-3), Thursday, 7:30 p.m.
Prediction: Memphis 31, Navy 27

Iowa (7-4) at Nebraska (7-4), Friday, Noon
Prediction: Iowa 24, Nebraska 13

Ohio (7-4) at Buffalo (5-6), Friday, Noon
Prediction: Ohio 23, Buffalo 20

Kent State (4-7) at Northern Illinois (3-8), Friday, Noon
Prediction: NIU 28, Kent State 21

Air Force (3-8) at Colorado State (2-9), Friday, 3 p.m.
Prediction: CSU 24, Air Force 21

Temple (5-6) at North Texas (10-1), Friday, 3:30 p.m.
Prediction: North Texas 40, Temple 24

San Diego State (9-2) at New Mexico (8-3), Friday, 3:30 p.m.
Prediction: SDSU 23, New Mexico 19

Boise State (7-4) at Utah State (6-5), Friday, 4 p.m.
Prediction: Boise State 32, Utah State 26

No. 25 Arizona (8-3) at No. 20 Arizona State (8-3), Friday, 9 p.m.
Prediction: Arizona 31, ASU 27

Saturday Early Games

3 of 5
BYU v Texas Tech
Jacob Rodriguez

No. 5 Texas Tech (10-1) at West Virginia (4-7), Noon ET

In the last month, West Virginia has started to compete much better with Big 12 opponents. The offense is still barely average at best, though, and that's not going to cut it against Texas Tech's top-10 defense. Short of Tech having a total outlier performance, this result won't be in question.

Prediction: Texas Tech 43, WVU 17

Central Florida (5-6) at No. 11 BYU (10-1), 1 p.m.

With a trip to the Big 12 Championship Game and its CFP life at stake, BYU also has a favorable finale. Last weekend—at home—UCF barely beat Oklahoma State. That result came on the heels of UCF's 39-point loss to Texas Tech. Anything is possible, sure, but BYU is a hefty favorite for good reason.

Prediction: BYU 36, UCF 13

Kentucky (5-6) at Louisville (7-4), Noon
Prediction: Louisville 27, Kentucky 20

Clemson (6-5) at South Carolina (4-7), Noon
Prediction: South Carolina 24, Clemson 23

Houston (8-3) at Baylor (5-6), Noon
Prediction: Baylor 34, Houston 30

Colorado (3-8) at Kansas State (5-6), Noon
Prediction: Kansas State 31, Colorado 24

Iowa State (7-4) at Oklahoma State (1-10), Noon
Prediction: Iowa State 27, Oklahoma State 13

East Carolina (7-4) at Florida Atlantic (4-7), Noon
Prediction: ECU 38, FAU 35

Toledo (7-4) at Central Michigan (7-4), Noon
Prediction: CMU 23, Toledo 20

Ball State (4-7) at Miami (Ohio) (6-5), Noon
Prediction: Miami 30, Ball State 10

UTEP (2-9) at Delaware (5-6), 1 p.m.
Prediction: Delaware 28, UTEP 17

Florida International (6-5) at Sam Houston (2-9), 1 p.m.
Prediction: FIU 31, Sam Houston 21

Georgia Southern (5-6) at Marshall (5-6), 1:30 p.m.
Prediction: Marshall 35, Georgia Southern 27

Western Kentucky (8-3) at Jacksonville State (7-4), 2 p.m.
Prediction: WKU 31, Jax State 28

Louisiana Tech (6-5) at Missouri State (7-4), 2 p.m.
Prediction: Missouri State 30, Louisiana Tech 24

Georgia State (1-10) at Old Dominion (8-3), 2 p.m.
Prediction: ODU 38, Georgia State 14

Arkansas State (5-6) at Appalachian State (5-6), 2:30 p.m.
Prediction: App State 31, Arkansas State 27

Boston College (1-10) at Syracuse (3-8), 3 p.m.
Prediction: Boston College 22, Syracuse 17

UAB (3-8) at Tulsa (4-7), 3 p.m.
Prediction: Tulsa 30, UAB 26

Middle Tennessee (2-9) at New Mexico State (4-7), 3 p.m.
Prediction: NMSU 29, MTSU 23

Louisiana-Monroe (3-8) at Louisiana (5-6), 3 p.m.
Prediction: Louisiana 33, ULM 20

South Alabama (4-7) at Texas State (5-6), 3 p.m.
Prediction: Texas State 36, South Alabama 24

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Saturday Afternoon Games

4 of 5
USC v Oregon
Dante Moore

No. 6 Oregon (10-1) at Washington (8-3), 3:30 p.m. ET

Flip the locations, and I would not hesitate. Washington cannot be trusted when it plays good competition outside of Seattle. At home, though? It's reason for pause. Washington QB Demond Williams Jr. generally has struggled with top defenses, and Oregon certainly fits the billing at 5.5 yards allowed per pass attempt. This would be a heck of a moment for Williams to break that trend.

Prediction: Oregon 27, Washington 17

LSU (7-4) at No. 8 Oklahoma (9-2), 3:30 p.m.

Speaking of trends, following a 13-10 win over Western Kentucky, LSU hasn't surpassed 25 points against an FBS opponent. I find it hard to believe that'll change at Oklahoma, which is ranked sixth nationally in scoring defense. LSU's defense is still fighting hard, but the Tigers just don't score enough.

Prediction: Oklahoma 24, LSU 13

UCLA (3-8) at No. 17 USC (8-3), 4:30 p.m.

Since a wild midseason surge, UCLA has faded back to reality with losses in four straight games—and three by 34 points or more. USC should hold a comfortable lead throughout the second half.

Prediction: USC 38, UCLA 17

Wake Forest (8-3) at Duke (6-5), 3:30 p.m.
Prediction: Wake Forest 29, Duke 24

Wisconsin (4-7) at Minnesota (6-5), 3:30 p.m.
Prediction: Minnesota 20, Wisconsin 17

Penn State (5-6) at Rutgers (5-6), 3:30 p.m.
Prediction: Penn State 38, Rutgers 24

Cincinnati (7-4) at TCU (7-4), 3:30 p.m.
Prediction: TCU 30, Cincinnati 27

Missouri (7-4) at Arkansas (2-9), 3:30 p.m.
Prediction: Arkansas 34, Missouri 31

Army (5-5) at UTSA (6-5), 3:30 p.m.
Prediction: UTSA 30, Army 28

Kennesaw State (8-3) at Liberty (4-7), 3:30 p.m.
Prediction: Kennesaw State 31, Liberty 23

Troy (7-4) at Southern Miss (7-4), 3:30 p.m.
Prediction: Troy 26, Southern Miss 23

James Madison (10-1) at Coastal Carolina (6-5), 3:45 p.m.
Prediction: JMU 45, Coastal Carolina 24

Florida State (5-6) at Florida (3-8), 4:30 p.m.
Prediction: Florida 23, FSU 20

Saturday Evening and Late Slate

5 of 5
COLLEGE FOOTBALL: NOV 22 Syracuse at Notre Dame
CJ Carr and Jeremiyah Love

Virginia Tech (3-8) at No. 18 Virginia (9-2), 7 p.m. ET

Virginia Tech has only two receivers with at least 200 yards this season, and the defense has created just six turnovers. Unless the Hokies find an outlier against UVA—which is solid in the secondary and rarely gives away possession—don't expect a VT upset that throws the ACC standings into chaos.

Prediction: Virginia 27, Virginia Tech 17

No. 10 Alabama (9-2) at Auburn (5-6), 7:30 p.m.

Alabama, obviously, is the better team. The year has stunk for Auburn, which is still a win shy of bowl eligibility. In comes Bama, the rival powerhouse on the verge of a CFP invite. Auburn has been a thorn when hosting the Iron Bowl for a decade, though, and its defense is seventh nationally in yards allowed per snap at home. Auburn, despite its awful season, gets a poll-shaking upset.

Prediction: Auburn 24, Alabama 20

Charlotte (1-10) at No. 24 Tulane (9-2), 7:30 p.m.

Needing a win to make the American Championship Game, Tulane could not have asked for a better conference matchup. Charlotte hasn't finished within 10 points of an FBS opponent all season.

Prediction: Tulane 38, Charlotte 14

No. 9 Notre Dame (9-2) at Stanford (4-7), 10:30 p.m.

Stanford has only allowed 123 rushing yards, excluding sacks, in the last two games. If there's any actual shot at springing the upset, it requires Stanford to slow ND's scorching ground game. Otherwise, it'll be ugly.

Prediction: Notre Dame 45, Stanford 7

Oregon State (2-9) at Washington State (5-6), 6:30 p.m.
Prediction: Washington State 27, Oregon State 19

Maryland (4-7) at Michigan State (3-8), 7 p.m.
Prediction: Maryland 24, MSU 22

Rice (5-6) at South Florida (8-3), 7 p.m.
Prediction: USF 45, Rice 21

North Carolina (4-7) at North Carolina State (6-5), 7:30 p.m.
Prediction: NC State 31, UNC 17

Northwestern (6-5) at Illinois (7-4), 7:30 p.m.
Prediction: Illinois 28, Northwestern 20

No. 21 SMU (8-3) at Cal (6-5), 8 p.m.
Prediction: SMU 27, Cal 22

UNLV (9-2) at Nevada (3-8), 9 p.m.
Prediction: UNLV 30, Nevada 20

Fresno State (7-4) at San Jose State (3-8), 10:30 p.m.
Prediction: Fresno State 27, SJSU 23

Wyoming (4-7) at Hawaii (7-4), 11 p.m.
Prediction: Hawaii 29, Wyoming 16

🚨 Mitchell Headed to 1st Conference Finals

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