Kansas City Chiefs quarterback Patrick Mahomes exited Saturday's divisional-round matchup against the Jacksonville Jaguars in the second quarter with an ankle injury and was replaced by Chad Henne before returning to start the second half.
NFL Network's Ian Rapoport reported that X-rays at halftime were negative, but it appears Mahomes suffered a high-ankle sprain.
ESPN's Adam Schefter reported Mahomes will undergo an MRI on Sunday to determine the injury's severity.
Mahomes suffered the injury during the first quarter when a Jaguars player landed on his leg while making a tackle. The Chiefs announced he was officially questionable to return.
Mahomes appeared in at least 14 games in each of the last four seasons after he became Kansas City's starter. His durability has helped him become one of the best quarterbacks in the league, and the result was four straight Pro Bowl appearances, a Super Bowl title and an MVP award during that stretch.
Mahomes has followed that with another impressive performance this year, completing 67.1 percent of his passes for 5,250 yards and 41 touchdowns against 12 interceptions, in addition to rushing for 358 yards and four scores en route to his fifth consecutive Pro Bowl selection.
Saturday's game against Jacksonville is Kansas City's first playoff game of the year after it earned a first-round bye as the AFC's top seed, finishing the regular season with a 14-3 record.
Henne finished the first half for the Chiefs, finding Travis Kelce on a 1-yard touchdown pass that concluded a 12-play, 98-yard drive.
Henne has experience in this type of situation. The 13-year veteran entered a playoff victory over the Cleveland Browns during the 2020 season when Mahomes was forced to exit. Henne even converted a fourth down at the end to preserve the win over Cleveland.