Buffalo Bills vs. Dallas Cowboys: Spread Info, Line and Predictions

The 2011 NFL season, replete with Super Bowl rematches to this point, will give football fans another blast from the past when the Dallas Cowboys and the Buffalo Bills meet in Irving, Texas on Sunday. Chances are, the game will be just a bit more competitive than it was back in 1993, when the Cowboys squashed the Bills for the second year in a row by a score of 52-17 at the Rose Bowl.

Well, at least Jim Kelly and the good folks of Buffalo are hoping the result is more favorable this time around.

Where: Cowboys Stadium, Irving, Texas

When: Sunday, November 13th at 1:00 p.m. EST

Watch: CBS

Spread: Cowboys -5.5 (according to sportsbook.com)

Take the Cowboys to beat the spread. Tony Romo and company figure to have a field day against Buffalo's lackluster defense, which should allow them to win by at least a touchdown, if not more.

Over/Under: 48 points (according to sportsbook.com)

Go with the over here. These two teams combine to average 50.2 points per game this season. There will be no shortage of scoring in this one, as both squads have plenty of playmakers who will find their way into the end zone.

Key Injuries:

The Bills will be severely shorthanded on defense and special teams on Sunday. Long-time placekicker Rian Lindell will sit out with a shoulder injury, while nose tackle Kyle Williams will miss the rest of the season after going on injured reserve with a knock to his left foot.

The Cowboys will once again be without running back Felix Jones (ankle) and wide receiver Miles Austin (hamstring). Dallas' secondary will also be missing one of its key cogs in cornerback Mike Jenkins (hamstring)

Fantasy Big Plays

START: DeMarco Murray, RB, Dallas Cowboys

Murray had another monster game last week against a solid Seahawks defense, piling up 186 total yards. He should find plenty more room to roam against Buffalo's resistance, which ranks in the bottom half of the league in run prevention.

SIT: Tony Romo, QB, Dallas Cowboys

As for Tony Romo, he may not be so lucky to have such a productive day while staring down that very same Bills defense, whose secondary has made a habit of forcing turnovers early and often this season. What's more, Romo hasn't cracked the 300-yard mark since mid-October.

START: David Nelson, WR, Buffalo Bills

Like most wideouts, Nelson struggled to get open against the Jets' shutdown corners but still managed to haul in four passes for 36 yards and a score. He should find life to be a bit easier against the Cowboys' defensive backfield, which has been banged up all season.

Keys to Buffalo Bills Win

Essentially, Buffalo must do on offense what it wants to prevent Dallas from doing with its defense—run the ball and protect the passer. The Bills need to establish the run with Fred Jackson to set the tempo, keep the Cowboys' offense off the field and protect Ryan Fitzpatrick from DeMarcus Ware and Dallas' furious pass rush. On the other side of things, the Bills need to keep Tony Romo on his toes and keep DeMarco Murray from gashing them for big gains.

Keys to Dallas Cowboys Win

Offensively, Dallas' success will be predicated on a balanced approach. So long as Romo is distributing the ball to his many targets and handing it off to Murray from time to time, the Cowboys should have little trouble marching down the field. Defensively, the Cowboys must get back to stopping the run, as they've proven to be susceptible to the ground game in recent weeks.

Prediction: Cowboys 31, Bills 27