The Pacers bested the Thunder 152-95 in Oklahoma City. The 57-point deficit is the largest regular-season road win in NBA history, according to Stat Perform.
Domantas Sabonis triple-doubled with 26 points, 19 rebounds and 14 assists.
What was more impressive about Sabonis' stat line is that he recorded the triple-double in the first half. The star had missed six consecutive games with a back injury heading into Saturday.
The game was never in reach for the Thunder, who trailed 82-46 at the break. And while the Pacers' domination was an NBA record, Oklahoma City didn't exactly put up much of a fight.
Indiana shot 65.5 percent from the field and 63.6 from deep, leading by as much as 67 points.
Doug McDermott dropped 31 points to lead all scorers, shooting 11-of-14 from the field and hitting six of eight attempts from three. For the Thunder, Moses Brown scored 16 points.
The Pacers improved to 30-33 with the win, good to maintain the ninth seed in the Eastern Conference. Meanwhile, the Thunder, who snapped a 14-game losing streak with a win against the Boston Celtics on Tuesday, have now dropped their last two games.
The Thunder are 21-43 and have already been eliminated from contention in the Western Conference.