This will mark the first game Love has sat out since returning to the lineup on April 1. He scored 18 points on 7-of-14 shooting in Wednesday's 141-105 loss to the Portland Trail Blazers.
A calf injury cost the five-time All-Star most of the first half of the season. He is averaging 12.8 points on 35.1 percent shooting from three-point range and 7.8 rebounds in 19 games since getting back in the lineup.
The Cavs aren't heading to the playoffs and have gotten used to playing without Love, so his absence will mark a return to the status quo. They are in the midst of an eight-game losing streak.
With Larry Nance Jr. still nursing a fractured thumb, Cavs head coach J.B. Bickerstaff will likely turn to Dean Wade as his primary power forward.