Tagovailoa went down after being tackled around the ankles by Volunteers defensive lineman Greg Emerson. He stayed in the game for one more play before being replaced by sophomore Mac Jones.
Tagovailoa was 11-of-12 passing for 155 yards, zero touchdowns and one interception.
The 21-year-old threw for 3,966 yards and 43 touchdowns against six interceptions in 2018, his first year as the full-time starting quarterback. His play suffered a bit toward the end of the season due to injuries, most notably an ankle problem that took him out of the SEC Championship Game against Georgia.
If Tagovailoa is forced to miss time, Mac Jones will take the reins as Alabama's starting quarterback.