Kalamian spent the past three seasons as an assistant in Toronto and has been an NBA assistant since the 1996-97 season.
His NBA career began with the Clippers, as he was with the organization from 1992 through 2003.
His status with the Raptors was in limbo after Toronto parted ways with head coach Dwane Casey.
Nick Nurse was reportedly promoted from assistant to head coach as Casey's replacement, but he won't have Kalamian on his staff.
Kalamian has spent time with several different organizations in addition to the Raptors and Clippers, including the Philadelphia 76ers (as a scout), Denver Nuggets, Minnesota Timberwolves, Sacramento Kings and Oklahoma City Thunder.
His greatest success as an assistant came in 2011-12 when he helped lead a Thunder team that included Kevin Durant, James Harden and Russell Westbrook to the NBA Finals.
OKC fell to LeBron James, Dwyane Wade, Chris Bosh and the Miami Heat.
In L.A., Kalamian will join a Clippers team that finished 42-40 last season and missed the playoffs for the first time since 2010-11.