John Brown Diagnosed with Sickle Cell Trait: Latest Details and Comments

Arizona Cardinals wide receiver John Brown's leg issues are the result of a sickle-cell trait. 

Per Darren Urban of the Cardinals' official website, Brown discovered the problem after undergoing a blood test. The team is working on addressing the problem. 

Per WebMD, sickle-cell trait occurs when a person inherits a sickle-cell gene from a single parent and is different from the disease because people with the trait have normal hemoglobin (hemoglobin A) and hemoglobin S. 

WebMD also notes that people with sickle-cell trait rarely have any symptoms but in certain rare cases may experience muscle pain or other potentially serious health problems that can occur due to intense exercise or being in high altitudes. 

Per the Cardinals' website, Brown has not practiced this week with what was originally listed as hamstring problems. Urban noted the team hasn't officially ruled out Brown for Sunday's game against the Seattle Seahawks yet, but his status will depend on how he feels.

Brown has appeared in each of the Cardinals' six games so far this season. He's averaging a career-low 12.5 yards per reception and has zero touchdown catches after recording 12 combined in the previous two seasons. 

Following an appearance in last year's NFC Championship Game, the Cardinals are off to a 3-3 start. Brown is one of their key offensive weapons, but his diagnosis could force the team to take him off the field until a solution to his sickle-cell trait is found.