NCAA Tournament Schedule 2012: Sweet 16 Upset Odds for Each No. 1 Seed

Despite all the craziness that has unfolded in the first three rounds of the NCAA tournament, the four No. 1-seeded teams are still standing.

The good news? That means a lot of brackets out there are still standing.

The bad news? There's no way this can last.

We're not going to see all four No. 1 seeds advance to the Final Four. The odds are against it, and my gut tells me it's not going to happen (I trust both equally). The question right now is whether all four No. 1 seeds will even be able to advance to the Elite Eight.

Since I'm not clairvoyant, I can't give you any prophecies. What I can do, however, is give you the odds of each No. 1 seed suffering an upset in the Sweet 16.

No. 4 Wisconsin vs. No. 1 Syracuse (Thursday at 7:15 p.m. ET)

The Orange should beware of this matchup. They've gotten this far without Fab Melo, and that's commendable, but Wisconsin is going to be a very tough team for them to beat.

The difficulty in playing the Badgers is scoring points against them. Wisconsin is the best defensive team in the country, and really forces teams to play their game. The Badgers don't suffer three-pointers to fall against them, meaning much of Syracuse's offense will have to come around the bucket.

The issue with Syracuse is that its halfcourt offense is decent at best, and getting buckets around the basket is going to be very difficult without Melo. If all goes well, the Orange will be able to get most of their buckets in transition, but that will be very hard to do against Wisconsin. The Badgers run a very slow, very efficient offense that isn't likely to give Syracuse too many transition opportunities.

Make no mistake about it, the odds of an upset in this game are very good.

Upset Odds: 5-to-2

No. 4 Louisville vs. No. 1 Michigan State (Thursday at 7:47 p.m. ET)

The Cardinals haven't had an easy path to the Sweet 16, but that shouldn't surprise anyone. Louisville is not equipped to blow opponents out—it's equipped to wear opponents down.

The Spartans will be a very tough team for Louisville to wear down, however. Michigan State does everything well, and it's led by a truly outstanding player in Draymond Green. There are few things he can't do on a basketball court, and it's going to be extremely difficult for Louisville to offset its presence.

To actually win this game, the Cardinals are going to have to pull off their best defensive effort of the season, which would be impressive given how well they play on defense. They'll also need Peyton Siva to be at his best, which he wasn't against New Mexico.

The Cardinals and Spartans aren't separated by much in terms of seeing, but there's no mistaking the fact that the Spartans have a lot more firepower. This is a game they should win.

Upset Odds: 13-to-1

No. 13 Ohio vs. No. 1 North Carolina (Friday at 7:47 p.m. ET)

It all depends on Kendall Marshall.

According to ESPN.com, Marshall is already wearing a removable cast mere days after having surgery to repair a fracture in his right wrist. There's a chance he'll be able to play, but Roy Williams is getting his team ready to play as if Marshall won't be there.

If Marshall misses this game, North Carolina is not going to run away with it. The Bobcats can't match up against Carolina's bigs and they'll have to worry about Harrison Barnes having an outstanding game, but they stand a much better chance of hanging with Carolina if Marshall doesn't play than they would if he does end up playing.

The truth is that all bets are off for Carolina if Marshall can't go. I, for one, highly doubt that Marshall actually will be able to play in this game, so I'm thinking the odds of an upset are quite good.

Upset Odds: 5-to-1

No. 4 Indiana vs. No. 1 Kentucky (Friday at 9:45 p.m. ET)

The Hoosiers are the only team that managed to beat Kentucky during the regular season, so the odds of an upset for this game have to be pretty good, right?

Not quite.

All things being equal, Kentucky has way more talent to work with than Indiana. Way back in early December, the Hoosiers won in large part because their home-court advantage leveled the playing field, and then they got a one-in-a-million shot from Christian Watford.

The Hoosiers will be able to compete in this game thanks to their three-point shooting. They're very good at knocking them down from distance, and that will allow them to avoid spending too much time in Anthony Davis' vicinity.

That's not going to be enough, though. The Wildcats are playing extremely well right now, and they'll be looking for revenge in this game. They stand a very good chance of getting it.

Upset Odds: 9-to-1