2022 NFL Schedule: Tom Brady, Bucs vs. Cowboys Highlights Complete Week 1 Slate

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The full 2022 NFL season schedule will be released on Thursday at 8 p.m. ET. However, we now know all of the Week 1 matchups thanks to early leaks and schedule updates throughout the day. 

The season will kick off with the Buffalo Bills traveling to face the Super Bowl champion Los Angeles Rams for Thursday Night Football, and Week 1 will conclude with the Seattle Seahawks hosting the Denver Broncos for Monday Night Football.

Bills vs. Rams

The Bills and Rams are expected to be two of the most exciting teams in football during the 2022 season, so it's no surprise they'll open the year on Thursday night. 

L.A. enters its second season with Matthew Stafford under center and will look to become the first team since the 2003 and 2004 New England Patriots to win back-to-back Super Bowl titles. 

The matchup will also mark Von Miller's return to L.A. The All-Pro pass rusher signed a six-year, $120 million deal with the Bills this offseason after spending the second half of the 2021 campaign with the Rams following a trade from the Broncos. 

Buffalo, meanwhile, enters the 2022 campaign after a disappointing overtime loss to the Kansas City Chiefs in the AFC Championship Game last season. That said, quarterback Josh Allen has been one of the best in the NFL over the last two years, and he and the Bills are on the verge of accomplishing something special.

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Buccaneers vs. Cowboys

For the second straight season, Tom Brady and the Buccaneers will meet Dak Prescott and the Dallas Cowboys in Week 1. The Bucs hosted the Cowboys at Raymond James Stadium in 2021, and now Dallas will host Tampa Bay at AT&T Stadium to open 2022. 

In last year's Week 1 meeting, Tom Brady threw for 379 yards and four touchdowns en route to a 31-29 victory. This year, Prescott will be looking to put up an impressive performance of his own to take down the seven-time Super Bowl champion. 

This matchup is particularly intriguing because Brady announced his retirement after the 2021 season before ultimately deciding to return for 2022 and finish out the remainder of his Buccaneers' contract. 

Brady will be looking to begin the season on a high note to set the tone for the remainder of the Bucs' season. 

Broncos vs. Seahawks

The Broncos and Seahawks meeting at Lumen Field to close out Week 1 only seems right. 

This matchup will mark Russell Wilson's return to Seattle after the Seahawks traded him to the Broncos this offseason, and it will be an emotional moment for both sides. 

That said, Wilson and the Broncos shouldn't have that difficult of a time against the Seahawks, who are expected to be led by quarterback Drew Lock. Seattle really hasn't done anything to improve its roster this offseason following the departure of Wilson, and it seems like only a matter of time before the franchise enters a rebuild.

Denver, meanwhile, is on the rise with Wilson under center and Nathaniel Hackett as head coach. The franchise has many of the tools needed to be successful, and getting a win right off the bat in Week 1 would be a major boost for the team.