NFL Picks Week 7: Colts-Saints Among Lots of Lopsided Matchups for Upcoming Week

Here's an early look at Week 7 games from the NFL and what teams are primed for big victories. 

Indianapolis Colts at New Orleans Saints

The Colts come into this one at 0-6 with no end to the win-less streak in sight. The Saints, on the other hand, just suffered a disappointing loss in Tampa Bay and will be looking to bounce back in a big way.

This one isn't going to be close. Indianapolis has come close to wins the last few weeks but just haven't been able to close out any games.

Having Curtis Painter behind center will do that to you.

The Saints have been less than spectacular on the defensive side of the ball, but Drew Brees should light up a Colts defense that has made guys like Matt Cassel and Andy Dalton look like Pro Bowlers.

This one will get ugly quickly.

Green Bay Packers at Minnesota Vikings

Best team in the NFL against quite possibly the worst. Uh-oh.

No one has been able to slow down Aaron Rodgers and the Green Bay Packers so far this season, and the Vikings certainly aren't going to be the first to do it.

Jay Cutler and the Bears just embarrassed the Vikes on Sunday Night Football. All due respect, but Mr. Cutler is not Aaron Rodgers.

The Vikings only chance to stay in this one is going to be to score 40 points. And with Donovan McNabb behind center, they likely won't get half that, even with Green Bay looking very beatable through the air. 

Atlanta Falcons at Detroit Lions

If anyone at the beginning of the season would have said this game is expected to be a blowout, you would have called them crazy. 

But the Falcons just haven't been able to get their offense in sync. Matt Ryan and Roddy White are having a tough time connecting like years past, and they were only able to hook up for two receptions against a weak Carolina defense.

A matchup against a Lions game coming off a disappointing loss won't be the thing to fix these problems.

The Lions have one of the best defensive lines in the league and likely won't let Matt Ryan and the offense get into sync. 

On the other side of the ball, the Falcons haven't been able to stop anyone, and things likely won't be different against Detroit. It's hard to imagine Jim Schwartz easing up on this one, and the Lions will put a lot of points on the board in a big win.