Ian Rapoport of NFL Network reported his status for Week 10 is "very much in doubt." Panthers head coach Matt Rhule would only say McCaffrey is "day-to-day" with the injury and that the running back is undergoing tests. The Panthers will know more about McCaffrey's status on Wednesday, per Rhule.
McCaffrey missed six games following a high ankle sprain in Week 2. Drafted out of Stanford by the Panthers with the eighth overall pick in 2017, he had never missed a game before the ankle injury.
Without the 2019 All-Pro on the field, the Panthers went 3-3 with three consecutive losses entering Week 9.
Prior to the ankle injury, McCaffrey served as Carolina's offensive focal point with 156 rushing yards and four touchdowns on 41 carries to go with 67 yards on seven catches. He was effective in his return, recording 151 total yards and two touchdowns.
In McCaffrey's absence, Mike Davis posted 349 rushing yards and two scores while adding 170 yards and two touchdowns on 30 catches through six starts. Should McCaffrey be sidelined, the South Carolina product—a fourth-round pick by the San Francisco 49ers in 2015—will see an increased role yet again.