The Los Angeles Angels, who hired La Russa as a senior adviser of baseball operations after the 2019 season, have given the White Sox permission to interview the 76-year-old for their managerial opening, according to Bob Nightengale of USA Today.
La Russa has not managed since the 2011 season.
La Russa started his managerial career with the White Sox in 1979. White Sox chairman Jerry Reinsdorf fired him during the 1986 season, a move he has said he regrets.
He won the World Series with the A's in 1989 and did so again with the Cardinals in 2006 and 2011. He also took home four Manager of the Year awards. He was inducted into the Hall of Fame in 2014 and has a 2,728-2,365 record as a manager.
Chicago has plenty of young talent and made the playoffs this year for the first time since 2008, but it hasn't won a postseason series since winning the World Series in 2005. La Russa has molded talented players into championship rosters before and may have the opportunity to do so where he started his managerial career.