According to Jason La Canfora of CBS Sports, the relationship between Williams and Washington "is totally fractured," with the seven-time Pro Bowler going as far as indicating he doesn't trust the medical team in place or team president Bruce Allen.
Williams also "made it known" he doesn't plan on playing for the NFC East team again.
This comes after Washington announced it signed offensive tackle Corey Robinson and placed Williams on the reserve/did not report list Saturday. Robinson appeared in four games for the Carolina Panthers and Jacksonville Jaguars last season.
Ian Rapoport of NFL.com provided additional details on Williams' situation, noting "there is no end in sight" for what looks to be a "lengthy and very complicated" holdout.
Rapoport said Williams "did not like how the medical staff handled his cancer scare last year" and eventually went to his own doctors, where he learned he had a precancerous growth on his scalp and underwent surgery.
The left tackle is also apparently frustrated with his contract situation.
Williams has been a staple of Washington's offensive line since it selected him with the No. 4 overall pick in the 2010 NFL draft. He played 13 games last season and earned an overall grade of 74.1 by Pro Football Focus' metrics.
Washington is moving into a new era with Dwayne Haskins under center as the quarterback of the future, and this adds a level of uncertainty to the five-man front that will be tasked with protecting him.
The O-line was a mere 26th in the league in run blocking and 24th in pass protection last season, per Football Outsiders, and figures to be one of the primary areas of concern heading into the new campaign.