Manchester United's trip to Manchester City on Sunday is the pick of the Premier League's Week 12 fixtures, as Jose Mourinho and Pep Guardiola renew their rivalry at the Etihad Stadium.
Chelsea head into the matchday in second place in the table, and Maurizio Sarri will be hoping his side can maintain their unbeaten start against Everton at Stamford Bridge.
Elsewhere, Liverpool face Fulham, Arsenal host Wolverhampton Wanderers and Tottenham Hotspur are away at Crystal Palace.
Saturday, November 10
12:30 p.m. BST, 7:30 a.m. ET: Cardiff City 0-1 Brighton & Hove Albion, Sky Sports Premier League (UK), NBCSN (U.S.)
3 p.m. BST, 10 a.m. ET: Huddersfield Town 1-2 West Ham United, NBC Sports Gold (U.S.)
3 p.m. BST, 10 a.m. ET: Leicester City 2-0 Burnley, NBCSN (U.S.)
3 p.m. BST, 10 a.m. ET: Newcastle 1-2 Bournemouth, NBC Sports Gold (U.S.)
3 p.m. BST, 10 a.m. ET: Southampton 0-2 Watford, NBC Sports Gold (U.S.)
5:30 p.m. BST, 12:30 p.m. ET: Crystal Palace 2-2 Tottenham, BT Sport 1 (UK), NBC (U.S.)
Sunday, November 11
12 p.m. GMT, 7 a.m. ET: Liverpool 4-0 Fulham, BT Sport 1 (UK) NBCSN (U.S.)
2:15 p.m. GMT, 9:15 a.m. ET: Chelsea 1-0 Everton, Sky Sports Premier League (UK), NBCSN(U.S.)
4:30 p.m. GMT, 11:30 ET: Arsenal 2-1 Wolves, NBC Sports Gold (U.S.)
4:30 p.m. GMT, 11:30 ET: Manchester City 3-1 Manchester United, Sky Sports Main Event (UK), NBCSN (U.S.)
Manchester City vs. Manchester United
The Etihad Stadium plays host to the first Manchester derby of the season on Sunday, and both teams head into the fixture in good form.
Manchester City have scored six goals in each of their past two outings, against Southampton and Shakhtar Donetsk, and they will take some stopping on home turf:
Yet Manchester United are fresh from an impressive 2-1 win over Juventus in the UEFA Champions League.
Alex Shaw at ESPN believes it's their best result under Mourinho:
The Red Devils can also take confidence from their most recent visit to the Etihad. The visitors were 2-0 down at half-time in April but came back to win 3-2 to delay City's title celebrations.
Manchester United have improved in recent weeks after a tough start. They were denied a win at Chelsea by a late equaliser and came from behind to beat Bournemouth last time out in the Premier League.
Football writer Daniel Harris noted their improvement:
However, a trip to the Premier League leaders will be their biggest challenge yet. Guardiola's side have not lost in the league this term and remain the team to beat.
Liverpool vs. Fulham
Goals will be expected at Anfield on Sunday, as the Premier League's leakiest defence takes on the Reds.
Fulham head into Week 12's fixtures bottom of the table, having conceded 29 goals in just 11 top-flight outings.
The Cottagers are on an awful run of form and have lost their past six games. Manager Slavisa Jokanovic is under pressure and has said his future is "outside of his control," per BBC Sport.
Liverpool will also need to improve following a disappointing 2-0 Champions League defeat to Red Star Belgrade.
Manager Jurgen Klopp offered his view after that match:
The Reds boss could look to change up his midfield to get his side back on track. Xherdan Shaqiri could be recalled to add creativity after missing the trip to Serbia, while Naby Keita may return after injury.
Fulham's visit offers Liverpool the perfect chance to bounce back before the international break. The Cottagers have looked out of their depth in the Premier League, and the Reds have the quality in attack to win comfortably.